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Comparison of risk scoring systems for critical care patients with upper gastrointestinal bleeding: predicting mortality and length of stay

BACKGROUND: Upper gastrointestinal bleeding (UGIB) is a common reason for intensive care admission. While there exist a number of UGIB scoring systems which are used to predict mortality, there are limited studies assessing the discriminative value of these scores in intensive care unit (ICU) patien...

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Autores principales: Lincoln, Marc, Keating, Niamh, O’Loughlin, Christopher, Tam, Angus, O’Kane, Molly Murphy, MacCarthy, Finbar, O’Connor, Enda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156557/
https://www.ncbi.nlm.nih.gov/pubmed/36345924
http://dx.doi.org/10.5114/ait.2022.120741
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author Lincoln, Marc
Keating, Niamh
O’Loughlin, Christopher
Tam, Angus
O’Kane, Molly Murphy
MacCarthy, Finbar
O’Connor, Enda
author_facet Lincoln, Marc
Keating, Niamh
O’Loughlin, Christopher
Tam, Angus
O’Kane, Molly Murphy
MacCarthy, Finbar
O’Connor, Enda
author_sort Lincoln, Marc
collection PubMed
description BACKGROUND: Upper gastrointestinal bleeding (UGIB) is a common reason for intensive care admission. While there exist a number of UGIB scoring systems which are used to predict mortality, there are limited studies assessing the discriminative value of these scores in intensive care unit (ICU) patients. The purpose of this study was to analyse five different UGIB scoring systems in predicting ICU mortality and length of stay and compare them to two commonly used ICU mortality scoring systems. METHODS: We retrospectively identified all patients requiring ICU admission for UGIB to St James’s Hospital over an 18-month period. We calculated their AIM65, Glasgow- Blatchford score, pre- and post-Rockall score, ABC, APACHE II and SOFA scores. We used area under the receiver operating characteristic curve (AUROC) to compare the predictive values of these six scoring systems for ICU and hospital mortality as well as ICU length of stay greater than seven days. RESULTS: APACHE II showed excellent discriminative value in predicting mortality in ICU patients (AUROC: 0.87; CI: 0.75–0.99) while the SOFA score showed good discriminative value (AUROC: 0.71; CI: 0.50–0.93). None of the UGIB scoring systems predicted mortality in these patients. All scoring systems showed poor discriminative value in predicting ICU length of stay. CONCLUSIONS: We were not able to validate any of these UGIB scoring systems for mortality or length of stay prediction in ICU patients. This study supports the validity of APACHE II as a clinical tool for predicting mortality in ICU patients with UGIB.
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spelling pubmed-101565572023-05-17 Comparison of risk scoring systems for critical care patients with upper gastrointestinal bleeding: predicting mortality and length of stay Lincoln, Marc Keating, Niamh O’Loughlin, Christopher Tam, Angus O’Kane, Molly Murphy MacCarthy, Finbar O’Connor, Enda Anaesthesiol Intensive Ther Original and Clinical Articles BACKGROUND: Upper gastrointestinal bleeding (UGIB) is a common reason for intensive care admission. While there exist a number of UGIB scoring systems which are used to predict mortality, there are limited studies assessing the discriminative value of these scores in intensive care unit (ICU) patients. The purpose of this study was to analyse five different UGIB scoring systems in predicting ICU mortality and length of stay and compare them to two commonly used ICU mortality scoring systems. METHODS: We retrospectively identified all patients requiring ICU admission for UGIB to St James’s Hospital over an 18-month period. We calculated their AIM65, Glasgow- Blatchford score, pre- and post-Rockall score, ABC, APACHE II and SOFA scores. We used area under the receiver operating characteristic curve (AUROC) to compare the predictive values of these six scoring systems for ICU and hospital mortality as well as ICU length of stay greater than seven days. RESULTS: APACHE II showed excellent discriminative value in predicting mortality in ICU patients (AUROC: 0.87; CI: 0.75–0.99) while the SOFA score showed good discriminative value (AUROC: 0.71; CI: 0.50–0.93). None of the UGIB scoring systems predicted mortality in these patients. All scoring systems showed poor discriminative value in predicting ICU length of stay. CONCLUSIONS: We were not able to validate any of these UGIB scoring systems for mortality or length of stay prediction in ICU patients. This study supports the validity of APACHE II as a clinical tool for predicting mortality in ICU patients with UGIB. Termedia Publishing House 2022-11-08 /pmc/articles/PMC10156557/ /pubmed/36345924 http://dx.doi.org/10.5114/ait.2022.120741 Text en Copyright © Polish Society of Anaesthesiology and Intensive Therapy https://creativecommons.org/licenses/by-nc-sa/4.0/This is an Open Access journal, all articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0). License (http://creativecommons.org/licenses/by-nc-sa/4.0/ (https://creativecommons.org/licenses/by-nc-sa/4.0/) ), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original and Clinical Articles
Lincoln, Marc
Keating, Niamh
O’Loughlin, Christopher
Tam, Angus
O’Kane, Molly Murphy
MacCarthy, Finbar
O’Connor, Enda
Comparison of risk scoring systems for critical care patients with upper gastrointestinal bleeding: predicting mortality and length of stay
title Comparison of risk scoring systems for critical care patients with upper gastrointestinal bleeding: predicting mortality and length of stay
title_full Comparison of risk scoring systems for critical care patients with upper gastrointestinal bleeding: predicting mortality and length of stay
title_fullStr Comparison of risk scoring systems for critical care patients with upper gastrointestinal bleeding: predicting mortality and length of stay
title_full_unstemmed Comparison of risk scoring systems for critical care patients with upper gastrointestinal bleeding: predicting mortality and length of stay
title_short Comparison of risk scoring systems for critical care patients with upper gastrointestinal bleeding: predicting mortality and length of stay
title_sort comparison of risk scoring systems for critical care patients with upper gastrointestinal bleeding: predicting mortality and length of stay
topic Original and Clinical Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156557/
https://www.ncbi.nlm.nih.gov/pubmed/36345924
http://dx.doi.org/10.5114/ait.2022.120741
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