Additive effects of intensive BP control and ACE inhibition on suppression of proteinuria in patients with CKD

The synergistic effects of RAAS inhibition and intensive blood pressure lowering in reducing proteinuria have not been well studied. We aimed to study this effect using data from the AASK Trial where our data suggest there is an additive and synergistic effect between RAAS inhibition and intensive b...

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Detalles Bibliográficos
Autores principales: Lopez, Rafael, Copeland, Timothy, McCulloch, Charles, Ku, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156588/
https://www.ncbi.nlm.nih.gov/pubmed/36966224
http://dx.doi.org/10.1038/s41371-023-00823-z
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author Lopez, Rafael
Copeland, Timothy
McCulloch, Charles
Ku, Elaine
author_facet Lopez, Rafael
Copeland, Timothy
McCulloch, Charles
Ku, Elaine
author_sort Lopez, Rafael
collection PubMed
description The synergistic effects of RAAS inhibition and intensive blood pressure lowering in reducing proteinuria have not been well studied. We aimed to study this effect using data from the AASK Trial where our data suggest there is an additive and synergistic effect between RAAS inhibition and intensive blood pressure inhibition in reducing proteinuria.
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spelling pubmed-101565882023-05-05 Additive effects of intensive BP control and ACE inhibition on suppression of proteinuria in patients with CKD Lopez, Rafael Copeland, Timothy McCulloch, Charles Ku, Elaine J Hum Hypertens Letter The synergistic effects of RAAS inhibition and intensive blood pressure lowering in reducing proteinuria have not been well studied. We aimed to study this effect using data from the AASK Trial where our data suggest there is an additive and synergistic effect between RAAS inhibition and intensive blood pressure inhibition in reducing proteinuria. Nature Publishing Group UK 2023-03-25 2023 /pmc/articles/PMC10156588/ /pubmed/36966224 http://dx.doi.org/10.1038/s41371-023-00823-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Letter
Lopez, Rafael
Copeland, Timothy
McCulloch, Charles
Ku, Elaine
Additive effects of intensive BP control and ACE inhibition on suppression of proteinuria in patients with CKD
title Additive effects of intensive BP control and ACE inhibition on suppression of proteinuria in patients with CKD
title_full Additive effects of intensive BP control and ACE inhibition on suppression of proteinuria in patients with CKD
title_fullStr Additive effects of intensive BP control and ACE inhibition on suppression of proteinuria in patients with CKD
title_full_unstemmed Additive effects of intensive BP control and ACE inhibition on suppression of proteinuria in patients with CKD
title_short Additive effects of intensive BP control and ACE inhibition on suppression of proteinuria in patients with CKD
title_sort additive effects of intensive bp control and ace inhibition on suppression of proteinuria in patients with ckd
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156588/
https://www.ncbi.nlm.nih.gov/pubmed/36966224
http://dx.doi.org/10.1038/s41371-023-00823-z
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AT mccullochcharles additiveeffectsofintensivebpcontrolandaceinhibitiononsuppressionofproteinuriainpatientswithckd
AT kuelaine additiveeffectsofintensivebpcontrolandaceinhibitiononsuppressionofproteinuriainpatientswithckd

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