Wisdom of the Crowd: insights gained from comparing predicted and observed effects of blood pressure lowering strategies

In a first of its kind assessment in cardiovascular research, we assessed whether pooled cardiovascular expertise could accurately predict efficacy and tolerability for both a novel and an established treatment option. A survey was administered prior to the publication of the QUARTET (A Quadruple Ul...

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Autores principales: Gnanenthiran, Sonali R., Jha, Vivekanand, Salam, Abdul, Atkins, Emily, Chow, Clara K., Nelson, Mark R., Rakotz, Mike, Schlaich, Markus P., Schutte, Aletta E., Usherwood, Tim, Rodgers, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156589/
https://www.ncbi.nlm.nih.gov/pubmed/37041253
http://dx.doi.org/10.1038/s41371-023-00816-y
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author Gnanenthiran, Sonali R.
Jha, Vivekanand
Salam, Abdul
Atkins, Emily
Chow, Clara K.
Nelson, Mark R.
Rakotz, Mike
Schlaich, Markus P.
Schutte, Aletta E.
Usherwood, Tim
Rodgers, Anthony
author_facet Gnanenthiran, Sonali R.
Jha, Vivekanand
Salam, Abdul
Atkins, Emily
Chow, Clara K.
Nelson, Mark R.
Rakotz, Mike
Schlaich, Markus P.
Schutte, Aletta E.
Usherwood, Tim
Rodgers, Anthony
author_sort Gnanenthiran, Sonali R.
collection PubMed
description In a first of its kind assessment in cardiovascular research, we assessed whether pooled cardiovascular expertise could accurately predict efficacy and tolerability for both a novel and an established treatment option. A survey was administered prior to the publication of the QUARTET (A Quadruple UltrA-low-dose tReatment for hypErTension) trial. QUARTET was a multicentre, double-blind, parallel-group, trial that randomised participants to initial treatment with either monotherapy or an ultra-low dose quadruple single pill combination for 12 weeks. Survey participants were asked to predict blood pressure (BP) at 12 weeks and 52 weeks for both groups.
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spelling pubmed-101565892023-05-05 Wisdom of the Crowd: insights gained from comparing predicted and observed effects of blood pressure lowering strategies Gnanenthiran, Sonali R. Jha, Vivekanand Salam, Abdul Atkins, Emily Chow, Clara K. Nelson, Mark R. Rakotz, Mike Schlaich, Markus P. Schutte, Aletta E. Usherwood, Tim Rodgers, Anthony J Hum Hypertens Letter In a first of its kind assessment in cardiovascular research, we assessed whether pooled cardiovascular expertise could accurately predict efficacy and tolerability for both a novel and an established treatment option. A survey was administered prior to the publication of the QUARTET (A Quadruple UltrA-low-dose tReatment for hypErTension) trial. QUARTET was a multicentre, double-blind, parallel-group, trial that randomised participants to initial treatment with either monotherapy or an ultra-low dose quadruple single pill combination for 12 weeks. Survey participants were asked to predict blood pressure (BP) at 12 weeks and 52 weeks for both groups. Nature Publishing Group UK 2023-04-11 2023 /pmc/articles/PMC10156589/ /pubmed/37041253 http://dx.doi.org/10.1038/s41371-023-00816-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Letter
Gnanenthiran, Sonali R.
Jha, Vivekanand
Salam, Abdul
Atkins, Emily
Chow, Clara K.
Nelson, Mark R.
Rakotz, Mike
Schlaich, Markus P.
Schutte, Aletta E.
Usherwood, Tim
Rodgers, Anthony
Wisdom of the Crowd: insights gained from comparing predicted and observed effects of blood pressure lowering strategies
title Wisdom of the Crowd: insights gained from comparing predicted and observed effects of blood pressure lowering strategies
title_full Wisdom of the Crowd: insights gained from comparing predicted and observed effects of blood pressure lowering strategies
title_fullStr Wisdom of the Crowd: insights gained from comparing predicted and observed effects of blood pressure lowering strategies
title_full_unstemmed Wisdom of the Crowd: insights gained from comparing predicted and observed effects of blood pressure lowering strategies
title_short Wisdom of the Crowd: insights gained from comparing predicted and observed effects of blood pressure lowering strategies
title_sort wisdom of the crowd: insights gained from comparing predicted and observed effects of blood pressure lowering strategies
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156589/
https://www.ncbi.nlm.nih.gov/pubmed/37041253
http://dx.doi.org/10.1038/s41371-023-00816-y
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