Tissue fluidification promotes a cGAS–STING cytosolic DNA response in invasive breast cancer

The process in which locally confined epithelial malignancies progressively evolve into invasive cancers is often promoted by unjamming, a phase transition from a solid-like to a liquid-like state, which occurs in various tissues. Whether this tissue-level mechanical transition impacts phenotypes du...

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Detalles Bibliográficos
Autores principales: Frittoli, Emanuela, Palamidessi, Andrea, Iannelli, Fabio, Zanardi, Federica, Villa, Stefano, Barzaghi, Leonardo, Abdo, Hind, Cancila, Valeria, Beznoussenko, Galina V., Della Chiara, Giulia, Pagani, Massimiliano, Malinverno, Chiara, Bhattacharya, Dipanjan, Pisati, Federica, Yu, Weimiao, Galimberti, Viviana, Bonizzi, Giuseppina, Martini, Emanuele, Mironov, Alexander A., Gioia, Ubaldo, Ascione, Flora, Li, Qingsen, Havas, Kristina, Magni, Serena, Lavagnino, Zeno, Pennacchio, Fabrizio Andrea, Maiuri, Paolo, Caponi, Silvia, Mattarelli, Maurizio, Martino, Sabata, d’Adda di Fagagna, Fabrizio, Rossi, Chiara, Lucioni, Marco, Tancredi, Richard, Pedrazzoli, Paolo, Vecchione, Andrea, Petrini, Cristiano, Ferrari, Francesco, Lanzuolo, Chiara, Bertalot, Giovanni, Nader, Guilherme, Foiani, Marco, Piel, Matthieu, Cerbino, Roberto, Giavazzi, Fabio, Tripodo, Claudio, Scita, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156599/
https://www.ncbi.nlm.nih.gov/pubmed/36581770
http://dx.doi.org/10.1038/s41563-022-01431-x

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