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A new acid isolated from V. negundo L. inhibits NLRP3 inflammasome activation and protects against inflammatory diseases

The NLRP3 inflammasome plays a critical role in the innate immune response, and its excessive activation will cause pyroptotic cell death and be associated with the onset of inflammatory diseases. However, NLRP3 inflammasome targeting therapies are still to be implemented in the clinic setting. Here...

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Detalles Bibliográficos
Autores principales: Di, Qianqian, Zhao, Xibao, Lin, Jing, Li, Xunwei, Li, Xiaoli, Tang, Haimei, Zhang, Ruihan, Xiao, Weilie, Chen, Weilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157029/
https://www.ncbi.nlm.nih.gov/pubmed/37153555
http://dx.doi.org/10.3389/fimmu.2023.1174463

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