Targeted locus amplification to develop robust patient-specific assays for liquid biopsies in pediatric solid tumors

BACKGROUND: Liquid biopsies combine minimally invasive sample collection with sensitive detection of residual disease. Pediatric malignancies harbor tumor-driving copy number alterations or fusion genes, rather than recurrent point mutations. These regions contain tumor-specific DNA breakpoint seque...

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Detalles Bibliográficos
Autores principales: van Zogchel, Lieke M. J., Lak, Nathalie S. M., Gelineau, Nina U., Sergeeva, Irina, Stelloo, Ellen, Swennenhuis, Joost, Feitsma, Harma, van Min, Max, Splinter, Erik, Bleijs, Margit, Groot Koerkamp, Marian, Breunis, Willemijn, Meister, Michael Torsten, Kholossy, Waleed Hassan, Holstege, Frank C. P., Molenaar, Jan J., de Leng, Wendy W. J., Stutterheim, Janine, van der Schoot, C. Ellen, Tytgat, Godelieve A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157037/
https://www.ncbi.nlm.nih.gov/pubmed/37152023
http://dx.doi.org/10.3389/fonc.2023.1124737

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