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The immunomodulatory effect of IL-4 accelerates bone substitute material-mediated osteogenesis in aged rats via NLRP3 inflammasome inhibition

BACKGROUND: Bone defect repair by implanting bone substitute materials has been a common clinical treatment. With the understanding of substance–immune system interactions and increasing evidence indicating that the post-implantation immune response determines the fate of bone substitute materials,...

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Detalles Bibliográficos
Autores principales: Li, Duchenhui, Li, Xiao, Zhang, Jie, Tang, Zhenglong, Tian, Ai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157059/
https://www.ncbi.nlm.nih.gov/pubmed/37153554
http://dx.doi.org/10.3389/fimmu.2023.1121549