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Pre- and post-treatment of α-Tocopherol on cognitive, synaptic plasticity, and mitochondrial disorders of the hippocampus in icv-streptozotocin-induced sporadic Alzheimer’s-like disease in male Wistar rat

OBJECTIVE: Most dementia cases in the elderly are caused by Alzheimer’s disease (AD), a complex, progressive neurological disease. Intracerebroventricular (ICV) administration of streptozotocin (STZ) in rat’s results in aberrant brain insulin signaling, oxidative stress, and mitochondrial dysfunctio...

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Detalles Bibliográficos
Autores principales: Nabavi Zadeh, Fatemeh, Nazari, Maryam, Amini, Abdollah, Adeli, Soheila, Barzegar Behrooz, Amir, Fahanik Babaei, Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157075/
https://www.ncbi.nlm.nih.gov/pubmed/37152606
http://dx.doi.org/10.3389/fnins.2023.1073369