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Vestibulocochlear Delineation for Vestibular Schwannoma Treated With Radiation Therapy

PURPOSE: To develop a specialist-based consensus of cochlear contouring to be used in patients undergoing stereotactic radiosurgery (SRS) treatment for vestibular schwannoma. METHODS AND MATERIALS: Representative computed tomography (CT) and magnetic resonance imaging (MRI) were used for cochlear co...

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Autores principales: Restini, Felipe Cicci Farinha, Brito, Leticia Hernandes, Yoshimoto, Fernanda Hayashida, Pereira, Ana Paula Alves, Neto, David Rodrigues Ferreira, Gomes, Vitor Cunha, Nascimento, Beatriz Cunha, Mancini, Anselmo, Alves, Tatiana Midori Martins Telles, Starling, Maria Thereza Mansur, Chaves, Guilherme Wilson Otaviano Garcia, Passos, Ula Lindoso, Marta, Gustavo Nader, Hanna, Samir Abdallah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157114/
https://www.ncbi.nlm.nih.gov/pubmed/37152490
http://dx.doi.org/10.1016/j.adro.2022.101171
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author Restini, Felipe Cicci Farinha
Brito, Leticia Hernandes
Yoshimoto, Fernanda Hayashida
Pereira, Ana Paula Alves
Neto, David Rodrigues Ferreira
Gomes, Vitor Cunha
Nascimento, Beatriz Cunha
Mancini, Anselmo
Alves, Tatiana Midori Martins Telles
Starling, Maria Thereza Mansur
Chaves, Guilherme Wilson Otaviano Garcia
Passos, Ula Lindoso
Marta, Gustavo Nader
Hanna, Samir Abdallah
author_facet Restini, Felipe Cicci Farinha
Brito, Leticia Hernandes
Yoshimoto, Fernanda Hayashida
Pereira, Ana Paula Alves
Neto, David Rodrigues Ferreira
Gomes, Vitor Cunha
Nascimento, Beatriz Cunha
Mancini, Anselmo
Alves, Tatiana Midori Martins Telles
Starling, Maria Thereza Mansur
Chaves, Guilherme Wilson Otaviano Garcia
Passos, Ula Lindoso
Marta, Gustavo Nader
Hanna, Samir Abdallah
author_sort Restini, Felipe Cicci Farinha
collection PubMed
description PURPOSE: To develop a specialist-based consensus of cochlear contouring to be used in patients undergoing stereotactic radiosurgery (SRS) treatment for vestibular schwannoma. METHODS AND MATERIALS: Representative computed tomography (CT) and magnetic resonance imaging (MRI) were used for cochlear contouring. The semicircles, cochlea, vestibule, and internal acoustic meatus were delineated by 7 radiation oncology department physicians and reviewed by neuroradiologists. A total of 12 cases accrued from a single academic institution were studied for a similarity analysis by the Dice coefficient. RESULTS: The suggested guideline is an easily reproductive tool that allows radiation oncologists to accurately contour the vestibulocochlear system to avoid toxicity due to inadequate dosimetry of organs at risk. This could be a useful tool even for non-vestibular schwannoma radiation therapy. The Dice coefficient suggests reproducible results as long as the following contouring recommendations are observed. CONCLUSIONS: The template for vestibulocochlear delineation may be useful for an adequate organs at risk definition. Future studies are required to find specific constraints for each segment of the vestibulocochlear system, and to mitigate interobserver variations.
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spelling pubmed-101571142023-05-05 Vestibulocochlear Delineation for Vestibular Schwannoma Treated With Radiation Therapy Restini, Felipe Cicci Farinha Brito, Leticia Hernandes Yoshimoto, Fernanda Hayashida Pereira, Ana Paula Alves Neto, David Rodrigues Ferreira Gomes, Vitor Cunha Nascimento, Beatriz Cunha Mancini, Anselmo Alves, Tatiana Midori Martins Telles Starling, Maria Thereza Mansur Chaves, Guilherme Wilson Otaviano Garcia Passos, Ula Lindoso Marta, Gustavo Nader Hanna, Samir Abdallah Adv Radiat Oncol Scientific Article PURPOSE: To develop a specialist-based consensus of cochlear contouring to be used in patients undergoing stereotactic radiosurgery (SRS) treatment for vestibular schwannoma. METHODS AND MATERIALS: Representative computed tomography (CT) and magnetic resonance imaging (MRI) were used for cochlear contouring. The semicircles, cochlea, vestibule, and internal acoustic meatus were delineated by 7 radiation oncology department physicians and reviewed by neuroradiologists. A total of 12 cases accrued from a single academic institution were studied for a similarity analysis by the Dice coefficient. RESULTS: The suggested guideline is an easily reproductive tool that allows radiation oncologists to accurately contour the vestibulocochlear system to avoid toxicity due to inadequate dosimetry of organs at risk. This could be a useful tool even for non-vestibular schwannoma radiation therapy. The Dice coefficient suggests reproducible results as long as the following contouring recommendations are observed. CONCLUSIONS: The template for vestibulocochlear delineation may be useful for an adequate organs at risk definition. Future studies are required to find specific constraints for each segment of the vestibulocochlear system, and to mitigate interobserver variations. Elsevier 2023-01-06 /pmc/articles/PMC10157114/ /pubmed/37152490 http://dx.doi.org/10.1016/j.adro.2022.101171 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Scientific Article
Restini, Felipe Cicci Farinha
Brito, Leticia Hernandes
Yoshimoto, Fernanda Hayashida
Pereira, Ana Paula Alves
Neto, David Rodrigues Ferreira
Gomes, Vitor Cunha
Nascimento, Beatriz Cunha
Mancini, Anselmo
Alves, Tatiana Midori Martins Telles
Starling, Maria Thereza Mansur
Chaves, Guilherme Wilson Otaviano Garcia
Passos, Ula Lindoso
Marta, Gustavo Nader
Hanna, Samir Abdallah
Vestibulocochlear Delineation for Vestibular Schwannoma Treated With Radiation Therapy
title Vestibulocochlear Delineation for Vestibular Schwannoma Treated With Radiation Therapy
title_full Vestibulocochlear Delineation for Vestibular Schwannoma Treated With Radiation Therapy
title_fullStr Vestibulocochlear Delineation for Vestibular Schwannoma Treated With Radiation Therapy
title_full_unstemmed Vestibulocochlear Delineation for Vestibular Schwannoma Treated With Radiation Therapy
title_short Vestibulocochlear Delineation for Vestibular Schwannoma Treated With Radiation Therapy
title_sort vestibulocochlear delineation for vestibular schwannoma treated with radiation therapy
topic Scientific Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157114/
https://www.ncbi.nlm.nih.gov/pubmed/37152490
http://dx.doi.org/10.1016/j.adro.2022.101171
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