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Design and selection of optimal ErbB-targeting bispecific antibodies in pancreatic cancer

The ErbB family of receptor tyrosine kinases is a primary target for small molecules and antibodies for pancreatic cancer treatment. Nonetheless, the current treatments for this tumor are not optimal due to lack of efficacy, resistance, or toxicity. Here, using the novel BiXAb™ tetravalent format pl...

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Detalles Bibliográficos
Autores principales:	Rabia, Emilia, Garambois, Véronique, Dhommée, Christine, Larbouret, Christel, Lajoie, Laurie, Buscail, Yoan, Jimenez-Dominguez, Gabriel, Choblet-Thery, Sylvie, Liaudet-Coopman, Emmanuelle, Cerutti, Martine, Jarlier, Marta, Ravel, Patrice, Gros, Laurent, Pirot, Nelly, Thibault, Gilles, Zhukovsky, Eugene A., Gérard, Pierre-Emmanuel, Pèlegrin, André, Colinge, Jacques, Chardès, Thierry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157173/ https://www.ncbi.nlm.nih.gov/pubmed/37153618 http://dx.doi.org/10.3389/fimmu.2023.1168444

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