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Small molecule glucagon release inhibitors with activity in human islets

PURPOSE: Type 1 diabetes (T1D) accounts for an estimated 5% of all diabetes in the United States, afflicting over 1.25 million individuals. Maintaining long-term blood glucose control is the major goal for individuals with T1D. In T1D, insulin-secreting pancreatic islet β-cells are destroyed by the...

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Detalles Bibliográficos
Autores principales:	Kalwat, Michael A., Rodrigues-dos-Santos, Karina, Binns, Derk D., Wei, Shuguang, Zhou, Anwu, Evans, Matthew R., Posner, Bruce A., Roth, Michael G., Cobb, Melanie H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157210/ https://www.ncbi.nlm.nih.gov/pubmed/37152965 http://dx.doi.org/10.3389/fendo.2023.1114799

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