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Limitations of human tau-expressing mouse models and novel approaches of mouse modeling for tauopathy
Neurofibrillary tangles (NFTs) composed of hyperphosphorylated tau protein are primarily neuropathological features of a number of neurodegenerative diseases, collectively termed tauopathy. There is no disease-modifying drug available for tauopathy except anti-amyloid antibody therapies for Alzheime...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157230/ https://www.ncbi.nlm.nih.gov/pubmed/37152607 http://dx.doi.org/10.3389/fnins.2023.1149761 |