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Enhancing physicians’ radiology diagnostics of COVID-19’s effects on lung health by leveraging artificial intelligence

Introduction: This study aimed to develop an individualized artificial intelligence model to help radiologists assess the severity of COVID-19’s effects on patients’ lung health. Methods: Data was collected from medical records of 1103 patients diagnosed with COVID-19 using RT- qPCR between March an...

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Autores principales: Gasulla, Óscar, Ledesma-Carbayo, Maria J., Borrell, Luisa N., Fortuny-Profitós, Jordi, Mazaira-Font, Ferran A., Barbero Allende, Jose María, Alonso-Menchén, David, García-Bennett, Josep, Del Río-Carrrero, Belen, Jofré-Grimaldo, Hector, Seguí, Aleix, Monserrat, Jorge, Teixidó-Román, Miguel, Torrent, Adrià, Ortega, Miguel Ángel, Álvarez-Mon, Melchor, Asúnsolo, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157246/
https://www.ncbi.nlm.nih.gov/pubmed/37152658
http://dx.doi.org/10.3389/fbioe.2023.1010679
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author Gasulla, Óscar
Ledesma-Carbayo, Maria J.
Borrell, Luisa N.
Fortuny-Profitós, Jordi
Mazaira-Font, Ferran A.
Barbero Allende, Jose María
Alonso-Menchén, David
García-Bennett, Josep
Del Río-Carrrero, Belen
Jofré-Grimaldo, Hector
Seguí, Aleix
Monserrat, Jorge
Teixidó-Román, Miguel
Torrent, Adrià
Ortega, Miguel Ángel
Álvarez-Mon, Melchor
Asúnsolo, Angel
author_facet Gasulla, Óscar
Ledesma-Carbayo, Maria J.
Borrell, Luisa N.
Fortuny-Profitós, Jordi
Mazaira-Font, Ferran A.
Barbero Allende, Jose María
Alonso-Menchén, David
García-Bennett, Josep
Del Río-Carrrero, Belen
Jofré-Grimaldo, Hector
Seguí, Aleix
Monserrat, Jorge
Teixidó-Román, Miguel
Torrent, Adrià
Ortega, Miguel Ángel
Álvarez-Mon, Melchor
Asúnsolo, Angel
author_sort Gasulla, Óscar
collection PubMed
description Introduction: This study aimed to develop an individualized artificial intelligence model to help radiologists assess the severity of COVID-19’s effects on patients’ lung health. Methods: Data was collected from medical records of 1103 patients diagnosed with COVID-19 using RT- qPCR between March and June 2020, in Hospital Madrid-Group (HM-Group, Spain). By using Convolutional Neural Networks, we determine the effects of COVID-19 in terms of lung area, opacities, and pulmonary air density. We then combine these variables with age and sex in a regression model to assess the severity of these conditions with respect to fatality risk (death or ICU). Results: Our model can predict high effect with an AUC of 0.736. Finally, we compare the performance of the model with respect to six physicians’ diagnosis, and test for improvements on physicians’ performance when using the prediction algorithm. Discussion: We find that the algorithm outperforms physicians (39.5% less error), and thus, physicians can significantly benefit from the information provided by the algorithm by reducing error by almost 30%.
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spelling pubmed-101572462023-05-05 Enhancing physicians’ radiology diagnostics of COVID-19’s effects on lung health by leveraging artificial intelligence Gasulla, Óscar Ledesma-Carbayo, Maria J. Borrell, Luisa N. Fortuny-Profitós, Jordi Mazaira-Font, Ferran A. Barbero Allende, Jose María Alonso-Menchén, David García-Bennett, Josep Del Río-Carrrero, Belen Jofré-Grimaldo, Hector Seguí, Aleix Monserrat, Jorge Teixidó-Román, Miguel Torrent, Adrià Ortega, Miguel Ángel Álvarez-Mon, Melchor Asúnsolo, Angel Front Bioeng Biotechnol Bioengineering and Biotechnology Introduction: This study aimed to develop an individualized artificial intelligence model to help radiologists assess the severity of COVID-19’s effects on patients’ lung health. Methods: Data was collected from medical records of 1103 patients diagnosed with COVID-19 using RT- qPCR between March and June 2020, in Hospital Madrid-Group (HM-Group, Spain). By using Convolutional Neural Networks, we determine the effects of COVID-19 in terms of lung area, opacities, and pulmonary air density. We then combine these variables with age and sex in a regression model to assess the severity of these conditions with respect to fatality risk (death or ICU). Results: Our model can predict high effect with an AUC of 0.736. Finally, we compare the performance of the model with respect to six physicians’ diagnosis, and test for improvements on physicians’ performance when using the prediction algorithm. Discussion: We find that the algorithm outperforms physicians (39.5% less error), and thus, physicians can significantly benefit from the information provided by the algorithm by reducing error by almost 30%. Frontiers Media S.A. 2023-04-20 /pmc/articles/PMC10157246/ /pubmed/37152658 http://dx.doi.org/10.3389/fbioe.2023.1010679 Text en Copyright © 2023 Gasulla, Ledesma-Carbayo, Borrell, Fortuny-Profitós, Mazaira-Font, Barbero Allende, Alonso-Menchén, García-Bennett, Del Río-Carrrero, Jofré-Grimaldo, Seguí, Monserrat, Teixidó-Román, Torrent, Ortega, Álvarez-Mon and Asúnsolo. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Gasulla, Óscar
Ledesma-Carbayo, Maria J.
Borrell, Luisa N.
Fortuny-Profitós, Jordi
Mazaira-Font, Ferran A.
Barbero Allende, Jose María
Alonso-Menchén, David
García-Bennett, Josep
Del Río-Carrrero, Belen
Jofré-Grimaldo, Hector
Seguí, Aleix
Monserrat, Jorge
Teixidó-Román, Miguel
Torrent, Adrià
Ortega, Miguel Ángel
Álvarez-Mon, Melchor
Asúnsolo, Angel
Enhancing physicians’ radiology diagnostics of COVID-19’s effects on lung health by leveraging artificial intelligence
title Enhancing physicians’ radiology diagnostics of COVID-19’s effects on lung health by leveraging artificial intelligence
title_full Enhancing physicians’ radiology diagnostics of COVID-19’s effects on lung health by leveraging artificial intelligence
title_fullStr Enhancing physicians’ radiology diagnostics of COVID-19’s effects on lung health by leveraging artificial intelligence
title_full_unstemmed Enhancing physicians’ radiology diagnostics of COVID-19’s effects on lung health by leveraging artificial intelligence
title_short Enhancing physicians’ radiology diagnostics of COVID-19’s effects on lung health by leveraging artificial intelligence
title_sort enhancing physicians’ radiology diagnostics of covid-19’s effects on lung health by leveraging artificial intelligence
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157246/
https://www.ncbi.nlm.nih.gov/pubmed/37152658
http://dx.doi.org/10.3389/fbioe.2023.1010679
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