The transcriptional regulator Sin3A balances IL‐17A and Foxp3 expression in primary CD4 T cells

The Sin3 transcriptional regulator homolog A (Sin3A) is the core member of a multiprotein chromatin‐modifying complex. Its inactivation at the CD4/CD8 double‐negative stage halts further thymocyte development. Among various functions, Sin3A regulates STAT3 transcriptional activity, central to the di...

Descripción completa

Detalles Bibliográficos
Autores principales: Perucho, Laura, Icardi, Laura, Di Simone, Elisabetta, Basso, Veronica, Agresti, Alessandra, Vilas Zornoza, Amaia, Lozano, Teresa, Prosper, Felipe, Lasarte, Juan José, Mondino, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157306/
https://www.ncbi.nlm.nih.gov/pubmed/36929576
http://dx.doi.org/10.15252/embr.202255326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157306/
https://www.ncbi.nlm.nih.gov/pubmed/36929576
http://dx.doi.org/10.15252/embr.202255326

Ejemplares similares