Cargando…

Resectability in bronchogenic carcinoma: A single‑center experience

Bronchogenic carcinoma comprises >90% of primary lung tumors. The present study aimed to estimate the profile of patients with bronchogenic carcinoma and assess the cancer resectability in newly diagnosed patients. This is a single-center retrospective review conducted over a period of 5 years. A...

Descripción completa

Detalles Bibliográficos
Autores principales: Marie, Mohammed Mowafaq, Jaber, Sabah N., Ahmed, Okba F., Kakamad, Fahmi H., Amin, Bnar J. Hama, Tahir, Soran H., Salih, Abdulwahid M., Abdalla, Shalaw H., Ali, Razhan K., Rashid, Rezheen J., Mohammed, Shvan H., Mustafa, Shevan M., Ali, Rebwar A., Rahim, Hawbash M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157354/
https://www.ncbi.nlm.nih.gov/pubmed/37153056
http://dx.doi.org/10.3892/ol.2023.13805
_version_ 1785036735138234368
author Marie, Mohammed Mowafaq
Jaber, Sabah N.
Ahmed, Okba F.
Kakamad, Fahmi H.
Amin, Bnar J. Hama
Tahir, Soran H.
Salih, Abdulwahid M.
Abdalla, Shalaw H.
Ali, Razhan K.
Rashid, Rezheen J.
Mohammed, Shvan H.
Mustafa, Shevan M.
Ali, Rebwar A.
Rahim, Hawbash M.
author_facet Marie, Mohammed Mowafaq
Jaber, Sabah N.
Ahmed, Okba F.
Kakamad, Fahmi H.
Amin, Bnar J. Hama
Tahir, Soran H.
Salih, Abdulwahid M.
Abdalla, Shalaw H.
Ali, Razhan K.
Rashid, Rezheen J.
Mohammed, Shvan H.
Mustafa, Shevan M.
Ali, Rebwar A.
Rahim, Hawbash M.
author_sort Marie, Mohammed Mowafaq
collection PubMed
description Bronchogenic carcinoma comprises >90% of primary lung tumors. The present study aimed to estimate the profile of patients with bronchogenic carcinoma and assess the cancer resectability in newly diagnosed patients. This is a single-center retrospective review conducted over a period of 5 years. A total of 800 patients with bronchogenic carcinoma were included. The diagnoses were mostly proven with either cytological examination or histopathological diagnosis. Sputum analysis, cytological examination of pleural effusion and bronchoscopic examination were performed. Lymph node biopsy, minimally invasive procedures (mediastinoscopy and video-assisted thoracoscopic surgery), tru-cut biopsy or fine-needle aspiration was used to obtain the samples for diagnosis. The masses were removed by lobectomy and pneumonectomy. The age range was between 22 and 87 years, with a mean age of 62.95 years. Males represented the predominant sex. Most of the patients were smokers or ex-smokers. The most common symptom was a cough, followed by dyspnea. Chest radiography revealed abnormal findings in 699 patients. A bronchoscopic evaluation was performed for the majority of patients (n=633). Endobronchial masses and other suggestive malignancy findings were present in 473 patients (83.1%) of the 569 who underwent fiberoptic bronchoscopy. Cytological and/or histopathological samples of 581 patients (91.8%) were positive. Small cell lung cancer (SCLC) occurred in 38 patients (4.75%) and non-SCLC was detected in 762 patients (95.25%). Lobectomy was the main surgical procedure, followed by pneumonectomy. A total of 5 patients developed postoperative complications without any mortality. In conclusion, bronchogenic carcinoma is rapidly increasing without a predilection for sex in the Iraqi population. Advanced preoperative staging and investigation tools are required to determine the rate of resectability.
format Online
Article
Text
id pubmed-10157354
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher D.A. Spandidos
record_format MEDLINE/PubMed
spelling pubmed-101573542023-05-05 Resectability in bronchogenic carcinoma: A single‑center experience Marie, Mohammed Mowafaq Jaber, Sabah N. Ahmed, Okba F. Kakamad, Fahmi H. Amin, Bnar J. Hama Tahir, Soran H. Salih, Abdulwahid M. Abdalla, Shalaw H. Ali, Razhan K. Rashid, Rezheen J. Mohammed, Shvan H. Mustafa, Shevan M. Ali, Rebwar A. Rahim, Hawbash M. Oncol Lett Articles Bronchogenic carcinoma comprises >90% of primary lung tumors. The present study aimed to estimate the profile of patients with bronchogenic carcinoma and assess the cancer resectability in newly diagnosed patients. This is a single-center retrospective review conducted over a period of 5 years. A total of 800 patients with bronchogenic carcinoma were included. The diagnoses were mostly proven with either cytological examination or histopathological diagnosis. Sputum analysis, cytological examination of pleural effusion and bronchoscopic examination were performed. Lymph node biopsy, minimally invasive procedures (mediastinoscopy and video-assisted thoracoscopic surgery), tru-cut biopsy or fine-needle aspiration was used to obtain the samples for diagnosis. The masses were removed by lobectomy and pneumonectomy. The age range was between 22 and 87 years, with a mean age of 62.95 years. Males represented the predominant sex. Most of the patients were smokers or ex-smokers. The most common symptom was a cough, followed by dyspnea. Chest radiography revealed abnormal findings in 699 patients. A bronchoscopic evaluation was performed for the majority of patients (n=633). Endobronchial masses and other suggestive malignancy findings were present in 473 patients (83.1%) of the 569 who underwent fiberoptic bronchoscopy. Cytological and/or histopathological samples of 581 patients (91.8%) were positive. Small cell lung cancer (SCLC) occurred in 38 patients (4.75%) and non-SCLC was detected in 762 patients (95.25%). Lobectomy was the main surgical procedure, followed by pneumonectomy. A total of 5 patients developed postoperative complications without any mortality. In conclusion, bronchogenic carcinoma is rapidly increasing without a predilection for sex in the Iraqi population. Advanced preoperative staging and investigation tools are required to determine the rate of resectability. D.A. Spandidos 2023-04-12 /pmc/articles/PMC10157354/ /pubmed/37153056 http://dx.doi.org/10.3892/ol.2023.13805 Text en Copyright: © Marie et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Marie, Mohammed Mowafaq
Jaber, Sabah N.
Ahmed, Okba F.
Kakamad, Fahmi H.
Amin, Bnar J. Hama
Tahir, Soran H.
Salih, Abdulwahid M.
Abdalla, Shalaw H.
Ali, Razhan K.
Rashid, Rezheen J.
Mohammed, Shvan H.
Mustafa, Shevan M.
Ali, Rebwar A.
Rahim, Hawbash M.
Resectability in bronchogenic carcinoma: A single‑center experience
title Resectability in bronchogenic carcinoma: A single‑center experience
title_full Resectability in bronchogenic carcinoma: A single‑center experience
title_fullStr Resectability in bronchogenic carcinoma: A single‑center experience
title_full_unstemmed Resectability in bronchogenic carcinoma: A single‑center experience
title_short Resectability in bronchogenic carcinoma: A single‑center experience
title_sort resectability in bronchogenic carcinoma: a single‑center experience
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157354/
https://www.ncbi.nlm.nih.gov/pubmed/37153056
http://dx.doi.org/10.3892/ol.2023.13805
work_keys_str_mv AT mariemohammedmowafaq resectabilityinbronchogeniccarcinomaasinglecenterexperience
AT jabersabahn resectabilityinbronchogeniccarcinomaasinglecenterexperience
AT ahmedokbaf resectabilityinbronchogeniccarcinomaasinglecenterexperience
AT kakamadfahmih resectabilityinbronchogeniccarcinomaasinglecenterexperience
AT aminbnarjhama resectabilityinbronchogeniccarcinomaasinglecenterexperience
AT tahirsoranh resectabilityinbronchogeniccarcinomaasinglecenterexperience
AT salihabdulwahidm resectabilityinbronchogeniccarcinomaasinglecenterexperience
AT abdallashalawh resectabilityinbronchogeniccarcinomaasinglecenterexperience
AT alirazhank resectabilityinbronchogeniccarcinomaasinglecenterexperience
AT rashidrezheenj resectabilityinbronchogeniccarcinomaasinglecenterexperience
AT mohammedshvanh resectabilityinbronchogeniccarcinomaasinglecenterexperience
AT mustafashevanm resectabilityinbronchogeniccarcinomaasinglecenterexperience
AT alirebwara resectabilityinbronchogeniccarcinomaasinglecenterexperience
AT rahimhawbashm resectabilityinbronchogeniccarcinomaasinglecenterexperience