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Resectability in bronchogenic carcinoma: A single‑center experience
Bronchogenic carcinoma comprises >90% of primary lung tumors. The present study aimed to estimate the profile of patients with bronchogenic carcinoma and assess the cancer resectability in newly diagnosed patients. This is a single-center retrospective review conducted over a period of 5 years. A...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157354/ https://www.ncbi.nlm.nih.gov/pubmed/37153056 http://dx.doi.org/10.3892/ol.2023.13805 |
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author | Marie, Mohammed Mowafaq Jaber, Sabah N. Ahmed, Okba F. Kakamad, Fahmi H. Amin, Bnar J. Hama Tahir, Soran H. Salih, Abdulwahid M. Abdalla, Shalaw H. Ali, Razhan K. Rashid, Rezheen J. Mohammed, Shvan H. Mustafa, Shevan M. Ali, Rebwar A. Rahim, Hawbash M. |
author_facet | Marie, Mohammed Mowafaq Jaber, Sabah N. Ahmed, Okba F. Kakamad, Fahmi H. Amin, Bnar J. Hama Tahir, Soran H. Salih, Abdulwahid M. Abdalla, Shalaw H. Ali, Razhan K. Rashid, Rezheen J. Mohammed, Shvan H. Mustafa, Shevan M. Ali, Rebwar A. Rahim, Hawbash M. |
author_sort | Marie, Mohammed Mowafaq |
collection | PubMed |
description | Bronchogenic carcinoma comprises >90% of primary lung tumors. The present study aimed to estimate the profile of patients with bronchogenic carcinoma and assess the cancer resectability in newly diagnosed patients. This is a single-center retrospective review conducted over a period of 5 years. A total of 800 patients with bronchogenic carcinoma were included. The diagnoses were mostly proven with either cytological examination or histopathological diagnosis. Sputum analysis, cytological examination of pleural effusion and bronchoscopic examination were performed. Lymph node biopsy, minimally invasive procedures (mediastinoscopy and video-assisted thoracoscopic surgery), tru-cut biopsy or fine-needle aspiration was used to obtain the samples for diagnosis. The masses were removed by lobectomy and pneumonectomy. The age range was between 22 and 87 years, with a mean age of 62.95 years. Males represented the predominant sex. Most of the patients were smokers or ex-smokers. The most common symptom was a cough, followed by dyspnea. Chest radiography revealed abnormal findings in 699 patients. A bronchoscopic evaluation was performed for the majority of patients (n=633). Endobronchial masses and other suggestive malignancy findings were present in 473 patients (83.1%) of the 569 who underwent fiberoptic bronchoscopy. Cytological and/or histopathological samples of 581 patients (91.8%) were positive. Small cell lung cancer (SCLC) occurred in 38 patients (4.75%) and non-SCLC was detected in 762 patients (95.25%). Lobectomy was the main surgical procedure, followed by pneumonectomy. A total of 5 patients developed postoperative complications without any mortality. In conclusion, bronchogenic carcinoma is rapidly increasing without a predilection for sex in the Iraqi population. Advanced preoperative staging and investigation tools are required to determine the rate of resectability. |
format | Online Article Text |
id | pubmed-10157354 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-101573542023-05-05 Resectability in bronchogenic carcinoma: A single‑center experience Marie, Mohammed Mowafaq Jaber, Sabah N. Ahmed, Okba F. Kakamad, Fahmi H. Amin, Bnar J. Hama Tahir, Soran H. Salih, Abdulwahid M. Abdalla, Shalaw H. Ali, Razhan K. Rashid, Rezheen J. Mohammed, Shvan H. Mustafa, Shevan M. Ali, Rebwar A. Rahim, Hawbash M. Oncol Lett Articles Bronchogenic carcinoma comprises >90% of primary lung tumors. The present study aimed to estimate the profile of patients with bronchogenic carcinoma and assess the cancer resectability in newly diagnosed patients. This is a single-center retrospective review conducted over a period of 5 years. A total of 800 patients with bronchogenic carcinoma were included. The diagnoses were mostly proven with either cytological examination or histopathological diagnosis. Sputum analysis, cytological examination of pleural effusion and bronchoscopic examination were performed. Lymph node biopsy, minimally invasive procedures (mediastinoscopy and video-assisted thoracoscopic surgery), tru-cut biopsy or fine-needle aspiration was used to obtain the samples for diagnosis. The masses were removed by lobectomy and pneumonectomy. The age range was between 22 and 87 years, with a mean age of 62.95 years. Males represented the predominant sex. Most of the patients were smokers or ex-smokers. The most common symptom was a cough, followed by dyspnea. Chest radiography revealed abnormal findings in 699 patients. A bronchoscopic evaluation was performed for the majority of patients (n=633). Endobronchial masses and other suggestive malignancy findings were present in 473 patients (83.1%) of the 569 who underwent fiberoptic bronchoscopy. Cytological and/or histopathological samples of 581 patients (91.8%) were positive. Small cell lung cancer (SCLC) occurred in 38 patients (4.75%) and non-SCLC was detected in 762 patients (95.25%). Lobectomy was the main surgical procedure, followed by pneumonectomy. A total of 5 patients developed postoperative complications without any mortality. In conclusion, bronchogenic carcinoma is rapidly increasing without a predilection for sex in the Iraqi population. Advanced preoperative staging and investigation tools are required to determine the rate of resectability. D.A. Spandidos 2023-04-12 /pmc/articles/PMC10157354/ /pubmed/37153056 http://dx.doi.org/10.3892/ol.2023.13805 Text en Copyright: © Marie et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Articles Marie, Mohammed Mowafaq Jaber, Sabah N. Ahmed, Okba F. Kakamad, Fahmi H. Amin, Bnar J. Hama Tahir, Soran H. Salih, Abdulwahid M. Abdalla, Shalaw H. Ali, Razhan K. Rashid, Rezheen J. Mohammed, Shvan H. Mustafa, Shevan M. Ali, Rebwar A. Rahim, Hawbash M. Resectability in bronchogenic carcinoma: A single‑center experience |
title | Resectability in bronchogenic carcinoma: A single‑center experience |
title_full | Resectability in bronchogenic carcinoma: A single‑center experience |
title_fullStr | Resectability in bronchogenic carcinoma: A single‑center experience |
title_full_unstemmed | Resectability in bronchogenic carcinoma: A single‑center experience |
title_short | Resectability in bronchogenic carcinoma: A single‑center experience |
title_sort | resectability in bronchogenic carcinoma: a single‑center experience |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157354/ https://www.ncbi.nlm.nih.gov/pubmed/37153056 http://dx.doi.org/10.3892/ol.2023.13805 |
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