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IMiDs Augment CD3-Bispecific Antibody–Induced CD8(+) T-Cell Cytotoxicity and Expansion by Enhancing IL2 Production

Although CD3-bispecific antibodies have shown promising activity in the treatment of hematological cancers, insufficient T-cell costimulation may limit long-term responses. Immunomodulatory drugs (IMiDs), routinely used in treating multiple myeloma, possess pleiotropic antimyeloma properties and hav...

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Detalles Bibliográficos
Autores principales:	Li, Ji, Slaga, Dionysos, Johnston, Jennifer, Junttila, Teemu T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2023
Materias:	Large Molecule Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157361/ https://www.ncbi.nlm.nih.gov/pubmed/36822576 http://dx.doi.org/10.1158/1535-7163.MCT-22-0498

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