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FAM69C functions as a kinase for eIF2α and promotes stress granule assembly

Stress granules are dynamic cytoplasmic ribonucleoprotein granules that assemble in response to cellular stress. Aberrant formation of stress granules has been linked to neurodegenerative diseases. However, the molecular mechanisms underlying the initiation of stress granules remain elusive. Here we...

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Detalles Bibliográficos
Autores principales: Wu, Zhongyan, Mei, Fan, Gan, Yangyang, Liu, Anhang, Hu, Jiapan, Jin, Yan, Yin, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157376/
https://www.ncbi.nlm.nih.gov/pubmed/36929224
http://dx.doi.org/10.15252/embr.202255641