Neuronal overexpression of hTDP-43 in Caenorhabditis elegans impairs different neuronally controlled behaviors and decreases fecundity

Cytoplasmic inclusions consisting of transactive response DNA-binding protein 43 (TDP-43) are a key hallmark of TDP-43 proteinopathies like amyotrophic lateral sclerosis (ALS). Caenorhabditis elegans is considered a useful model for studying the molecular mechanisms underlying TDP-43 toxicity in viv...

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Detalles Bibliográficos
Autores principales: Koopman, Mandy, Güngördü, Lale, Seinstra, Renée I., Nollen, Ellen A.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2023
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157382/
https://www.ncbi.nlm.nih.gov/pubmed/37151215
http://dx.doi.org/10.17912/micropub.biology.000769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157382/
https://www.ncbi.nlm.nih.gov/pubmed/37151215
http://dx.doi.org/10.17912/micropub.biology.000769

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