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The miR-27a-3p/FTO axis modifies hypoxia-induced malignant behaviors of glioma cells: miR-27a-3p/FTO affects glioma growth

Glioblastoma multiforme (GBM) is one of the most malignant types of central nervous system (CNS) tumors. N6-methyladenine (m6A) RNA modification is a main type of RNA modification in eukaryotic cells. In this study, we find that the m6A RNA methylation eraser FTO is dramatically downregulated in gli...

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Detalles Bibliográficos
Autores principales: Du, Peng, Meng, Li, Liao, Xinbin, Liu, Yi, Mo, Xin, Gong, Mengqi, Liao, Yiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157519/
https://www.ncbi.nlm.nih.gov/pubmed/36718644
http://dx.doi.org/10.3724/abbs.2023002