Cargando…

Lpcat3 deficiency promotes palmitic acid-induced 3T3-L1 mature adipocyte inflammation through enhanced ROS generation: Lpcat3 deficiency promotes adipocyte inflammation

Phosphatidylcholines (PCs) are major phospholipids in the mammalian cell membrane. Structural remodeling of PCs is associated with many biological processes. Lysophosphatidylcholine acyltransferase 3 (Lpcat3), which catalyzes the incorporation of polyunsaturated fatty acyl chains into the sn-2 site...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Jiachun, Deng, Yan, Ding, Tingbo, Dong, Jibin, Liang, Yuning, Lou, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157521/ https://www.ncbi.nlm.nih.gov/pubmed/36331295 http://dx.doi.org/10.3724/abbs.2022161

Ejemplares similares

LPCAT1 overexpression promotes the progression of hepatocellular carcinoma
por: He, Rong-Quan, et al.
Publicado: (2021)

Comprehensive Analysis of LPCATs Highlights the Prognostic and Immunological Values of LPCAT1/4 in Hepatocellular Carcinoma
por: Lin, Tong, et al.
Publicado: (2021)

ROBO4 deletion ameliorates PAF-mediated skin inflammation via regulating the mRNA translation efficiency of LPCAT1/LPCAT2 and the expression of PAF receptor
por: Xiao, Xiaoqiang, et al.
Publicado: (2020)

Research progress in the role and mechanism of LPCAT3 in metabolic related diseases and cancer
por: Shao, Gaoxuan, et al.
Publicado: (2022)

Ferroptosis-related genes LPCAT3 and PGD are potential diagnostic biomarkers for osteoarthritis
por: Wang, Lufei, et al.
Publicado: (2023)

Pan-cancer analysis identifies LPCATs family as a prognostic biomarker and validation of LPCAT4/WNT/β-catenin/c-JUN/ACSL3 in hepatocellular carcinoma
por: Lu, Yaoyong, et al.
Publicado: (2023)

Overexpression of LPCAT1 enhances endometrial cancer stemness and metastasis by changing lipid components and activating TGF-β/Smad2/3 signaling pathway: Tumor-promoting effect of LPCAT1 in endometrial cancer
por: Zhao, Tianyi, et al.
Publicado: (2022)

LPCAT2 controls chemoresistance in colorectal cancer
por: Cotte, Alexia Karen, et al.
Publicado: (2018)

Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion
por: Rong, Xin, et al.
Publicado: (2015)

Coronaviral Main Protease Induces LPCAT3 Cleavage and Endoplasmic Reticulum (ER) Stress
por: Wang, Jia, et al.
Publicado: (2023)

LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-regulating PI3K/AKT/MYC pathway
por: Wei, Chunhua, et al.
Publicado: (2019)

Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport
por: Hashidate-Yoshida, Tomomi, et al.
Publicado: (2015)

LPCAT1 reprogramming cholesterol metabolism promotes the progression of esophageal squamous cell carcinoma
por: Tao, Mingyue, et al.
Publicado: (2021)

LPCAT1 promotes gefitinib resistance via upregulation of the EGFR/PI3K/AKT signaling pathway in lung adenocarcinoma
por: Ding, Jianghua, et al.
Publicado: (2022)

Liver-specific overexpression of LPCAT3 reduces postprandial hyperglycemia and improves lipoprotein metabolic profile in mice
por: Cash, J G, et al.
Publicado: (2016)

LPCAT1 is transcriptionally regulated by FOXA1 to promote breast cancer progression and paclitaxel resistance
por: Zhang, Huayi, et al.
Publicado: (2023)

Palmitate induces endoplasmic reticulum stress and autophagy in mature adipocytes: Implications for apoptosis and inflammation
por: YIN, JIAJING, et al.
Publicado: (2015)

LpCat1 Promotes Malignant Transformation of Hepatocellular Carcinoma Cells by Directly Suppressing STAT1
por: Ji, Weidan, et al.
Publicado: (2021)

LPCAT1 controls phosphate homeostasis in a zinc-dependent manner
por: Kisko, Mushtak, et al.
Publicado: (2018)

Qinggan Huoxue Recipe Alleviates Alcoholic Liver Injury by Suppressing Endoplasmic Reticulum Stress Through LXR-LPCAT3
por: Lu, Yifei, et al.
Publicado: (2022)

Phosphatidylcholine formation by LPCAT1 is regulated by Ca(2+) and the redox status of the cell
por: Soupene, Eric, et al.
Publicado: (2012)

LPCAT1 functions as a novel prognostic molecular marker in hepatocellular carcinoma
por: Zhang, Hongbin, et al.
Publicado: (2020)

LPCAT4 Knockdown Alters Barrier Integrity and Cellular Bioenergetics in Human Urothelium
por: Mason, Andrew S., et al.
Publicado: (2022)

LPCAT1 acts as an independent prognostic biomarker correlated with immune infiltration in hepatocellular carcinoma
por: Li, Lan, et al.
Publicado: (2022)

Bilobalide Induces Apoptosis in 3T3-L1 Mature Adipocytes through ROS-Mediated Mitochondria Pathway
por: Bu, Su, et al.
Publicado: (2023)

Up-regulation of lysophosphatidylcholine acyltransferase 1 (LPCAT1) is linked to poor prognosis in breast cancer
por: Lebok, Patrick, et al.
Publicado: (2019)

Mitochondrial Reactive Oxygen Species Formation Determines ACSL4/LPCAT2-Mediated Ferroptosis
por: Merkel, Melanie, et al.
Publicado: (2023)

Effect of saccharin on inflammation in 3T3-L1 adipocytes and the related mechanism
por: Kim, Hye Lin, et al.
Publicado: (2020)

LPCAT3 is a potential prognostic biomarker and may be correlated with immune infiltration and ferroptosis in acute myeloid leukemia: a pan-cancer analysis
por: Ke, Peng, et al.
Publicado: (2022)

Downregulation of circLPAR3 inhibits tumor progression and glycolysis by liberating miR‐144‐3p and upregulating LPCAT1 in oral squamous cell carcinoma
por: Su, Zhijian, et al.
Publicado: (2022)

Resveratrol Metabolites Modify Adipokine Expression and Secretion in 3T3-L1 Pre-Adipocytes and Mature Adipocytes
por: Eseberri, Itziar, et al.
Publicado: (2013)

Suppressing adipocyte inflammation promotes insulin resistance in mice
por: Zhu, Qingzhang, et al.
Publicado: (2020)

Impaired phosphocreatine metabolism in white adipocytes promotes inflammation
por: Maqdasy, Salwan, et al.
Publicado: (2022)

The Effects of Triterpenoid Saponins from the Seeds of Momordica cochinchinensis on Adipocyte Differentiation and Mature Adipocyte Inflammation
por: Yu, Jae Sik, et al.
Publicado: (2020)

PAR2 Deficiency Induces Mitochondrial ROS Generation and Dysfunctions, Leading to the Inhibition of Adipocyte Differentiation
por: Park, Yeo Jin, et al.
Publicado: (2021)

Plant Acyl-CoA:Lysophosphatidylcholine Acyltransferases (LPCATs) Have Different Specificities in Their Forward and Reverse Reactions
por: Lager, Ida, et al.
Publicado: (2013)

LPCAT1-TERT fusions are uniquely recurrent in epithelioid trophoblastic tumors and positively regulate cell growth
por: Oliver, Gavin R., et al.
Publicado: (2021)

Elevated expression of LPCAT1 predicts a poor prognosis and is correlated with the tumour microenvironment in endometrial cancer
por: Zhao, Tianyi, et al.
Publicado: (2021)

LPCAT1 enhances the invasion and migration in gastric cancer: Based on computational biology methods and in vitro experiments
por: Chen, Zu‐Xuan, et al.
Publicado: (2023)

Paprika Pigments Attenuate Obesity-Induced Inflammation in 3T3-L1 Adipocytes
por: Maeda, Hayato, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_e1h27hpd1c3l112comaa77ucm8