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COM33 suppresses carboplatin-induced epithelial-mesenchymal transition via inhibition of Twist1 in ovarian cancer: COM33 sensitizes ovarian cancer to carboplatin
Despite favorable responses to platinum-based chemotherapy in ovarian cancer (OC), chemoresistance is still a major cause of treatment failure. Hence, we develop a novel synthetic agent, COM33, to relieve the chemoresistance caused by carboplatin. The anti-cancerous effects of the combination of COM...
Autores principales: | Zhou, Zhiyang, Jin, Li, Shen, Jian, Shi, Weihui, Xu, Yue, Ye, Longyun, Liu, Junxi, Pan, Jiexue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157527/ https://www.ncbi.nlm.nih.gov/pubmed/36647720 http://dx.doi.org/10.3724/abbs.2022195 |
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