A novel alkaloid compound, DCZ0358, exerts significant antitumor activity in bortezomib-resistant multiple myeloma cells through inhibition of JAK2/STAT3 pathway: Anti-myeloma activity of a novel alkaloid in drug-resistant cells

Multiple myeloma (MM), the seco nd most common haematological malignancy, is currently incurable because patients often develop multiple drug resistance and experience subsequent relapse of the disease. This study aims to identify a potential therapeutic agent that can counter bortezomib (BTZ) resis...

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Detalles Bibliográficos
Autores principales: Zhang, Bibo, Li, Bo, Xie, Yongsheng, Chang, Shuaikang, Xu, Zhijian, Hu, Huifang, Chen, Gege, Zhang, Ting, He, Jun, Wu, Xiaosong, Zhu, Huabin, Lai, Weiming, Song, Dongliang, Lu, Ying, Jia, Xinyan, Zhu, Weiliang, Shi, Jumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157528/
https://www.ncbi.nlm.nih.gov/pubmed/36815376
http://dx.doi.org/10.3724/abbs.2023014

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