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Cycloheximide promotes type I collagen maturation mainly via collagen prolyl 4-hydroxylase subunit α2: Cycloheximide promotes type I collagen proline hydroxylation

Aberrant deposition of collagen is associated with cancer development and tissue fibrosis. Proline hydroxylation, catalyzed by collagen prolyl 4-hydroxylases (C-P4Hs), is necessary for collagen maturation and secretion. Here, we try to evaluate the mechanism of the regulation of CHX on collagen matu...

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Detalles Bibliográficos
Autores principales:	Shi, Run, Xu, Miao, Ye, Huazhe, Gao, Shanshan, Li, Jingfeng, Li, Huan, Li, Chaoyang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157532/ https://www.ncbi.nlm.nih.gov/pubmed/36789685 http://dx.doi.org/10.3724/abbs.2022191

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