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USP9x promotes CD8 (+) T-cell dysfunction in association with autophagy inhibition in septic liver injury : USP9x inhibits CD8 (+) T cell autophagy in septic liver injury
Sepsis is a life-threatening condition manifested by concurrent inflammation and immunosuppression. Ubiquitin-specific peptidase 9, X-linked (USP9x), is a USP domain-containing deubiquitinase which is required in T-cell development. In the present study, we investigate whether USP9x plays a role in...
Autores principales: | Sheng, Lulu, Chen, Juntao, Tong, Yiqing, Zhang, Yi, Feng, Qiming, Tang, Zhenghao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157537/ https://www.ncbi.nlm.nih.gov/pubmed/36514222 http://dx.doi.org/10.3724/abbs.2022174 |
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