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Gαi1/3 mediate Netrin-1-CD146-activated signaling and angiogenesis

Netrin-1 binds to the high-affinity receptor CD146 to activate downstream signaling and angiogenesis. Here, we examine the role and underlying mechanisms of G protein subunit alpha i1 (Gαi1) and Gαi3 in Netrin-1-induced signaling and pro-angiogenic activity. In mouse embryonic fibroblasts (MEFs) and...

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Detalles Bibliográficos
Autores principales: Li, Ya, Chai, Jin-long, Shi, Xin, Feng, Yu, Li, Jia-jun, Zhou, Li-na, Cao, Cong, Li, Ke-ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157725/
https://www.ncbi.nlm.nih.gov/pubmed/37153740
http://dx.doi.org/10.7150/thno.80749