Gli1 promotes the phenotypic transformation of valve interstitial cells through Hedgehog pathway activation exacerbating calcific aortic valve disease

Calcific aortic valve disease (CAVD) is the most prevalent human valve disease worldwide. Multiple factors induce "irreversible" pathological changes in the aortic valve leaflets, resulting in changes in cardiac hemodynamics, eventually leading to heart failure. However, no effective pharm...

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Detalles Bibliográficos
Autores principales: Huang, Yuming, Jiang, Chen, Chen, Liang, Han, Juanjuan, Liu, Ming, Zhou, Tingwen, Dong, Nianguo, Xu, Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158026/
https://www.ncbi.nlm.nih.gov/pubmed/37151880
http://dx.doi.org/10.7150/ijbs.74123

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