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A Co-diagnosis of Crohn Disease and Autoimmune Diabetes in an Adolescent Patient

Inflammatory bowel disease (IBD) is a lifelong, immune-mediated disorder that often occurs in childhood and is becoming increasingly common worldwide. Diagnosis of IBD in children remains difficult due to the spectrum of symptoms, including gastrointestinal and extraintestinal manifestations. Type 1...

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Autores principales: Chranioti, Ioanna, Vartzelis, George, Maritsi, Despoina, Tsolia, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158271/
https://www.ncbi.nlm.nih.gov/pubmed/37168469
http://dx.doi.org/10.1097/PG9.0000000000000265
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author Chranioti, Ioanna
Vartzelis, George
Maritsi, Despoina
Tsolia, Maria
author_facet Chranioti, Ioanna
Vartzelis, George
Maritsi, Despoina
Tsolia, Maria
author_sort Chranioti, Ioanna
collection PubMed
description Inflammatory bowel disease (IBD) is a lifelong, immune-mediated disorder that often occurs in childhood and is becoming increasingly common worldwide. Diagnosis of IBD in children remains difficult due to the spectrum of symptoms, including gastrointestinal and extraintestinal manifestations. Type 1 diabetes mellitus (T1D) is one of the most common autoimmune diseases in children and adolescents. Classic manifestations of T1D in young people include polyuria, polydipsia, abdominal pain, weight loss, and ketoacidosis. However, children with autoimmunity of pancreatic β-cells may remain euglycemic and asymptomatic for many years. An accurate and prompt diagnosis of IBD and T1D is particularly important in children because they can negatively affect growth, psychosocial function and overall well-being. We present a case in which a previously healthy child was co-diagnosed with Crohn disease and T1D during a routine pediatric evaluation in the outpatient clinic of a peripheral secondary hospital.
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spelling pubmed-101582712023-05-09 A Co-diagnosis of Crohn Disease and Autoimmune Diabetes in an Adolescent Patient Chranioti, Ioanna Vartzelis, George Maritsi, Despoina Tsolia, Maria JPGN Rep Case Report Inflammatory bowel disease (IBD) is a lifelong, immune-mediated disorder that often occurs in childhood and is becoming increasingly common worldwide. Diagnosis of IBD in children remains difficult due to the spectrum of symptoms, including gastrointestinal and extraintestinal manifestations. Type 1 diabetes mellitus (T1D) is one of the most common autoimmune diseases in children and adolescents. Classic manifestations of T1D in young people include polyuria, polydipsia, abdominal pain, weight loss, and ketoacidosis. However, children with autoimmunity of pancreatic β-cells may remain euglycemic and asymptomatic for many years. An accurate and prompt diagnosis of IBD and T1D is particularly important in children because they can negatively affect growth, psychosocial function and overall well-being. We present a case in which a previously healthy child was co-diagnosed with Crohn disease and T1D during a routine pediatric evaluation in the outpatient clinic of a peripheral secondary hospital. Lippincott Williams & Wilkins, Inc. 2022-10-20 /pmc/articles/PMC10158271/ /pubmed/37168469 http://dx.doi.org/10.1097/PG9.0000000000000265 Text en Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Chranioti, Ioanna
Vartzelis, George
Maritsi, Despoina
Tsolia, Maria
A Co-diagnosis of Crohn Disease and Autoimmune Diabetes in an Adolescent Patient
title A Co-diagnosis of Crohn Disease and Autoimmune Diabetes in an Adolescent Patient
title_full A Co-diagnosis of Crohn Disease and Autoimmune Diabetes in an Adolescent Patient
title_fullStr A Co-diagnosis of Crohn Disease and Autoimmune Diabetes in an Adolescent Patient
title_full_unstemmed A Co-diagnosis of Crohn Disease and Autoimmune Diabetes in an Adolescent Patient
title_short A Co-diagnosis of Crohn Disease and Autoimmune Diabetes in an Adolescent Patient
title_sort co-diagnosis of crohn disease and autoimmune diabetes in an adolescent patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158271/
https://www.ncbi.nlm.nih.gov/pubmed/37168469
http://dx.doi.org/10.1097/PG9.0000000000000265
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