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Unifocal Gastric Langerhans Cell Histiocytosis in a Child—A Unique Case to Remember
Langerhans cell histiocytosis (LCH) is the most common of the histiocytic disorders and occurs when the body accumulates too many CD1a/CD 207 positive Langerhans cells, a subset of the histiocytes in certain parts of the body where they can form tumors or damage organs. LCH is not a very common diag...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158364/ https://www.ncbi.nlm.nih.gov/pubmed/37168914 http://dx.doi.org/10.1097/PG9.0000000000000192 |
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author | Acharyya, Bhaswati C. Roy, Mandira Chakraborty, Hema |
author_facet | Acharyya, Bhaswati C. Roy, Mandira Chakraborty, Hema |
author_sort | Acharyya, Bhaswati C. |
collection | PubMed |
description | Langerhans cell histiocytosis (LCH) is the most common of the histiocytic disorders and occurs when the body accumulates too many CD1a/CD 207 positive Langerhans cells, a subset of the histiocytes in certain parts of the body where they can form tumors or damage organs. LCH is not a very common diagnosis in the pediatric age group. More than two-thirds of cases have the single-system disease with bones or skin as the commonly involved sites. Here, we present a 4-year-old child who had acute abdominal pain as chief complaint and etiological workup eventually led to a diagnosis of gastric LCH without affection of any other organ system. To the best of our knowledge, this is the first report of a unifocal gastric LCH in a child. |
format | Online Article Text |
id | pubmed-10158364 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Lippincott Williams & Wilkins, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-101583642023-05-09 Unifocal Gastric Langerhans Cell Histiocytosis in a Child—A Unique Case to Remember Acharyya, Bhaswati C. Roy, Mandira Chakraborty, Hema JPGN Rep Case Report Langerhans cell histiocytosis (LCH) is the most common of the histiocytic disorders and occurs when the body accumulates too many CD1a/CD 207 positive Langerhans cells, a subset of the histiocytes in certain parts of the body where they can form tumors or damage organs. LCH is not a very common diagnosis in the pediatric age group. More than two-thirds of cases have the single-system disease with bones or skin as the commonly involved sites. Here, we present a 4-year-old child who had acute abdominal pain as chief complaint and etiological workup eventually led to a diagnosis of gastric LCH without affection of any other organ system. To the best of our knowledge, this is the first report of a unifocal gastric LCH in a child. Lippincott Williams & Wilkins, Inc. 2022-03-17 /pmc/articles/PMC10158364/ /pubmed/37168914 http://dx.doi.org/10.1097/PG9.0000000000000192 Text en Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Case Report Acharyya, Bhaswati C. Roy, Mandira Chakraborty, Hema Unifocal Gastric Langerhans Cell Histiocytosis in a Child—A Unique Case to Remember |
title | Unifocal Gastric Langerhans Cell Histiocytosis in a Child—A Unique Case to Remember |
title_full | Unifocal Gastric Langerhans Cell Histiocytosis in a Child—A Unique Case to Remember |
title_fullStr | Unifocal Gastric Langerhans Cell Histiocytosis in a Child—A Unique Case to Remember |
title_full_unstemmed | Unifocal Gastric Langerhans Cell Histiocytosis in a Child—A Unique Case to Remember |
title_short | Unifocal Gastric Langerhans Cell Histiocytosis in a Child—A Unique Case to Remember |
title_sort | unifocal gastric langerhans cell histiocytosis in a child—a unique case to remember |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158364/ https://www.ncbi.nlm.nih.gov/pubmed/37168914 http://dx.doi.org/10.1097/PG9.0000000000000192 |
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