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CircREOS suppresses lipid synthesis and osteosarcoma progression through inhibiting HuR-mediated MYC activation

MYC proto-oncogene (MYC) is a transcription factor among the most commonly activated oncoproteins, playing vital roles in lipid metabolism and tumor aggressiveness with broad effects. However, it is still largely unknown about the regulating mechanisms of MYC in osteosarcoma (OS). In this study, we...

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Detalles Bibliográficos
Autores principales: Tong, Weilai, Wang, Shijiang, He, Cheng, Li, Anan, Nie, Jiangbo, Zuo, Wei, Yang, Feng, Liu, Zhili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158517/
https://www.ncbi.nlm.nih.gov/pubmed/37151387
http://dx.doi.org/10.7150/jca.83106