Crohn’s disease proteolytic microbiota enhances inflammation through PAR2 pathway in gnotobiotic mice

Emerging evidence implicates microbial proteolytic activity in ulcerative colitis (UC), but whether it also plays a role in Crohn’s disease (CD) remains unclear. We investigated the effects of colonizing adult and neonatal germ-free C57BL/6 mice with CD microbiota, selected based on high (CD-HPA) or...

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Detalles Bibliográficos
Autores principales: Santiago, Alba, Hann, Amber, Constante, Marco, Rahmani, Sara, Libertucci, Josie, Jackson, Kyle, Rueda, Gaston, Rossi, Laura, Ramachandran, Rithwik, Ruf, Wolfram, Schertzer, Jon, Caminero, Alberto, Bercik, Premysl, Galipeau, Heather Jean, Verdu, Elena Francisca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158566/
https://www.ncbi.nlm.nih.gov/pubmed/37131291
http://dx.doi.org/10.1080/19490976.2023.2205425

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