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Targeting XBP1 mRNA splicing sensitizes glioblastoma to chemotherapy

Glioblastoma (GBM) is the most frequent and deadly primary brain tumor in adults. Temozolomide (TMZ) is the standard systemic therapy in GBM but has limited and restricted efficacy. Better treatments are urgently needed. The role of endoplasmic reticulum stress (ER stress) is increasingly described...

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Detalles Bibliográficos
Autores principales:	Dowdell, Amiee, Marsland, Mark, Faulkner, Sam, Gedye, Craig, Lynam, James, Griffin, Cassandra P., Marsland, Joanne, Jiang, Chen Chen, Hondermarck, Hubert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158625/ https://www.ncbi.nlm.nih.gov/pubmed/37151848 http://dx.doi.org/10.1096/fba.2022-00141

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