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Highly efficient and rapid generation of genetic variants
A new mutagenesis platform enables the fast, cost-efficient and automatable production of defined multi-site sequence variants for a wide range of applications. Demonstrations of this method included the generation of SARS-CoV-2 spike gene variants, DNA fragments for large-scale genome engineering,...
Formato: | Online Artículo Texto |
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Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158673/ https://www.ncbi.nlm.nih.gov/pubmed/37142768 http://dx.doi.org/10.1038/s41592-023-01869-0 |