An instrument-free, programmable approach for nucleic acid detection

INSPECTR is a technique for detecting nucleic acids that couples the sensitivity and specificity of nucleic acid splinted ligation with the versatile readouts of cell-free gene expression. The result is an ambient-temperature workflow that enables the detection of pathogenic viruses at low copy numb...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Research Briefing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158681/
https://www.ncbi.nlm.nih.gov/pubmed/37142845
http://dx.doi.org/10.1038/s41551-023-01041-1
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description INSPECTR is a technique for detecting nucleic acids that couples the sensitivity and specificity of nucleic acid splinted ligation with the versatile readouts of cell-free gene expression. The result is an ambient-temperature workflow that enables the detection of pathogenic viruses at low copy numbers.
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spelling pubmed-101586812023-05-09 An instrument-free, programmable approach for nucleic acid detection Nat Biomed Eng Research Briefing INSPECTR is a technique for detecting nucleic acids that couples the sensitivity and specificity of nucleic acid splinted ligation with the versatile readouts of cell-free gene expression. The result is an ambient-temperature workflow that enables the detection of pathogenic viruses at low copy numbers. Nature Publishing Group UK 2023-05-04 /pmc/articles/PMC10158681/ /pubmed/37142845 http://dx.doi.org/10.1038/s41551-023-01041-1 Text en © The Author(s), under exclusive licence to Springer Nature Limited 2023 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Research Briefing
An instrument-free, programmable approach for nucleic acid detection
title An instrument-free, programmable approach for nucleic acid detection
title_full An instrument-free, programmable approach for nucleic acid detection
title_fullStr An instrument-free, programmable approach for nucleic acid detection
title_full_unstemmed An instrument-free, programmable approach for nucleic acid detection
title_short An instrument-free, programmable approach for nucleic acid detection
title_sort instrument-free, programmable approach for nucleic acid detection
topic Research Briefing
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158681/
https://www.ncbi.nlm.nih.gov/pubmed/37142845
http://dx.doi.org/10.1038/s41551-023-01041-1

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