Cargando…

Thromboprophylaxis for Coagulopathy Related to COVID-19 in Pediatrics: A Narrative Review

In addition to harming the respiratory system, COVID-19 can affect multiple organs. Children may develop a specific complication of COVID-19 called multisystem inflammatory syndrome in children (MIS-C) which could influence the vascular system of children and cause multiple coagulopathies in the bod...

Descripción completa

Detalles Bibliográficos
Autores principales: Sahrai, Hadi, Hemmati-Ghavshough, Mahdi, Shahrabi, Marzieh, Jafari-Rouhi, Amir Hossein, Solduzian, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158690/
https://www.ncbi.nlm.nih.gov/pubmed/37142896
http://dx.doi.org/10.1007/s40272-023-00566-x
_version_ 1785036981983510528
author Sahrai, Hadi
Hemmati-Ghavshough, Mahdi
Shahrabi, Marzieh
Jafari-Rouhi, Amir Hossein
Solduzian, Mohammad
author_facet Sahrai, Hadi
Hemmati-Ghavshough, Mahdi
Shahrabi, Marzieh
Jafari-Rouhi, Amir Hossein
Solduzian, Mohammad
author_sort Sahrai, Hadi
collection PubMed
description In addition to harming the respiratory system, COVID-19 can affect multiple organs. Children may develop a specific complication of COVID-19 called multisystem inflammatory syndrome in children (MIS-C) which could influence the vascular system of children and cause multiple coagulopathies in the body. Information on the use of thromboprophylaxis in this condition was collected via the review of various articles. In general, different factors in immune system responses can trigger the initiation of thrombotic events. Studies have shown that starting anticoagulant prophylaxis, which contributes to decreased thrombotic events, is dependent on the patient's condition and D-dimer levels. However, further studies on pediatric populations are needed to establish the role of anticoagulants in children with this condition.
format Online
Article
Text
id pubmed-10158690
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Springer International Publishing
record_format MEDLINE/PubMed
spelling pubmed-101586902023-05-09 Thromboprophylaxis for Coagulopathy Related to COVID-19 in Pediatrics: A Narrative Review Sahrai, Hadi Hemmati-Ghavshough, Mahdi Shahrabi, Marzieh Jafari-Rouhi, Amir Hossein Solduzian, Mohammad Paediatr Drugs Review Article In addition to harming the respiratory system, COVID-19 can affect multiple organs. Children may develop a specific complication of COVID-19 called multisystem inflammatory syndrome in children (MIS-C) which could influence the vascular system of children and cause multiple coagulopathies in the body. Information on the use of thromboprophylaxis in this condition was collected via the review of various articles. In general, different factors in immune system responses can trigger the initiation of thrombotic events. Studies have shown that starting anticoagulant prophylaxis, which contributes to decreased thrombotic events, is dependent on the patient's condition and D-dimer levels. However, further studies on pediatric populations are needed to establish the role of anticoagulants in children with this condition. Springer International Publishing 2023-05-04 /pmc/articles/PMC10158690/ /pubmed/37142896 http://dx.doi.org/10.1007/s40272-023-00566-x Text en © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review Article
Sahrai, Hadi
Hemmati-Ghavshough, Mahdi
Shahrabi, Marzieh
Jafari-Rouhi, Amir Hossein
Solduzian, Mohammad
Thromboprophylaxis for Coagulopathy Related to COVID-19 in Pediatrics: A Narrative Review
title Thromboprophylaxis for Coagulopathy Related to COVID-19 in Pediatrics: A Narrative Review
title_full Thromboprophylaxis for Coagulopathy Related to COVID-19 in Pediatrics: A Narrative Review
title_fullStr Thromboprophylaxis for Coagulopathy Related to COVID-19 in Pediatrics: A Narrative Review
title_full_unstemmed Thromboprophylaxis for Coagulopathy Related to COVID-19 in Pediatrics: A Narrative Review
title_short Thromboprophylaxis for Coagulopathy Related to COVID-19 in Pediatrics: A Narrative Review
title_sort thromboprophylaxis for coagulopathy related to covid-19 in pediatrics: a narrative review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158690/
https://www.ncbi.nlm.nih.gov/pubmed/37142896
http://dx.doi.org/10.1007/s40272-023-00566-x
work_keys_str_mv AT sahraihadi thromboprophylaxisforcoagulopathyrelatedtocovid19inpediatricsanarrativereview
AT hemmatighavshoughmahdi thromboprophylaxisforcoagulopathyrelatedtocovid19inpediatricsanarrativereview
AT shahrabimarzieh thromboprophylaxisforcoagulopathyrelatedtocovid19inpediatricsanarrativereview
AT jafarirouhiamirhossein thromboprophylaxisforcoagulopathyrelatedtocovid19inpediatricsanarrativereview
AT solduzianmohammad thromboprophylaxisforcoagulopathyrelatedtocovid19inpediatricsanarrativereview