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Cell‐free chromatin immunoprecipitation can determine tumor gene expression in lung cancer patients

Cell‐free DNA (cfDNA) in blood plasma can be bound to nucleosomes that contain post‐translational modifications representing the epigenetic profile of the cell of origin. This includes histone H3 lysine 36 trimethylation (H3K36me3), a marker of active transcription. We hypothesised that cell‐free ch...

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Detalles Bibliográficos
Autores principales:	Trier Maansson, Christoffer, Meldgaard, Peter, Stougaard, Magnus, Nielsen, Anders Lade, Sorensen, Boe Sandahl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158780/ https://www.ncbi.nlm.nih.gov/pubmed/36825535 http://dx.doi.org/10.1002/1878-0261.13394

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