Overexpressed PKM2 promotes macrophage phagocytosis and atherosclerosis

BACKGROUND: The expression of pyruvate kinase muscle 2 (PKM2) is augmented in macrophages of patients with atherosclerotic coronary artery disease. The role of PKM2 in atherosclerosis is to be determined. METHODS: Global and myeloid cell‐specific PKM2 knock‐in mice with ApoE ( −/− ) background (ApoE...

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Detalles Bibliográficos
Autores principales: Gai, Xiaochen, Liu, Fangming, Wu, Yuting, Zhang, Baohui, Tang, Bufu, Shang, Kezhuo, Wang, Lianmei, Zhang, Haihong, Chen, Yixin, Yang, Shuhui, Deng, Weiwei, Li, Peng, Wang, Jing, Zhang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Themed Section: Study on Cardiovascular and Cerebrovascular Diseases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158947/
https://www.ncbi.nlm.nih.gov/pubmed/35974691
http://dx.doi.org/10.1002/ame2.12266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10158947/
https://www.ncbi.nlm.nih.gov/pubmed/35974691
http://dx.doi.org/10.1002/ame2.12266

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