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Structural analysis of MALAT1 long noncoding RNA in cells and in evolution

Although not canonically polyadenylated, the long noncoding RNA MALAT1 (metastasis-associated lung adenocarcinoma transcript 1) is stabilized by a highly conserved 76-nt triple helix structure on its 3′ end. The entire MALAT1 transcript is over 8000 nt long in humans. The strongest structural conser...

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Detalles Bibliográficos
Autores principales: Monroy-Eklund, Anais, Taylor, Colin, Weidmann, Chase A., Burch, Christina, Laederach, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159000/
https://www.ncbi.nlm.nih.gov/pubmed/36792358
http://dx.doi.org/10.1261/rna.079388.122