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Identification of the pore-forming and binding domains of the Sneathia vaginalis cytopathogenic toxin A
The association between Sneathia vaginalis and preterm birth is emerging. The Gram-negative anaerobe produces a large exotoxin, the cytopathogenic toxin A (CptA), that forms pores in human epithelial cells and red blood cells. The structure of the toxin has not been determined, but in silico analysi...
Autores principales: | O’Brien, Cathyrn K., Raskin, Jacob R., Amankwa Asare, Ivypel, Wei, Christine, Ma, Joy, McCoy, Zion T., Jefferson, Kimberly K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159106/ https://www.ncbi.nlm.nih.gov/pubmed/37141247 http://dx.doi.org/10.1371/journal.pone.0284349 |
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