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Plasmodium falciparum-infected erythrocyte co-culture with the monocyte cell line THP-1 does not trigger production of soluble factors reducing brain microvascular barrier function

Monocytes contribute to the pro-inflammatory immune response during the blood stage of a Plasmodium falciparum infection, but their precise role in malaria pathology is not clear. Besides phagocytosis, monocytes are activated by products from P. falciparum infected erythrocytes (IE) and one of the a...

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Detalles Bibliográficos
Autores principales: Storm, Janet, Camarda, Grazia, Haley, Michael J., Brough, David, Couper, Kevin N., Craig, Alister G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159134/
https://www.ncbi.nlm.nih.gov/pubmed/37141324
http://dx.doi.org/10.1371/journal.pone.0285323