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A case report of conus intramedullary mansoni neuroschistosomiasis

BACKGROUND: Conus schistosomiasis is an extremely rare entity in which patients present with a wide range of neurological symptoms such as low back pain, paresthesia, fever, myalgia, paraparesis, and paraplegia. This neglected tropical parasitic disease causes significant neurological morbidity. The...

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Autores principales: Mohandas, Prithvi, Sarkar, Hrishikesh, Jain, Deepti, Sundaram, Vanaja Kate Garfin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159276/
https://www.ncbi.nlm.nih.gov/pubmed/37151453
http://dx.doi.org/10.25259/SNI_47_2023
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author Mohandas, Prithvi
Sarkar, Hrishikesh
Jain, Deepti
Sundaram, Vanaja Kate Garfin
author_facet Mohandas, Prithvi
Sarkar, Hrishikesh
Jain, Deepti
Sundaram, Vanaja Kate Garfin
author_sort Mohandas, Prithvi
collection PubMed
description BACKGROUND: Conus schistosomiasis is an extremely rare entity in which patients present with a wide range of neurological symptoms such as low back pain, paresthesia, fever, myalgia, paraparesis, and paraplegia. This neglected tropical parasitic disease causes significant neurological morbidity. The migration of parasitic worms and their eggs into the central nervous system can lead to profound and life-altering disabilities. Early, accurate diagnosis, and treatment can lead to the complete resolution of symptoms. CASE DESCRIPTION: A 5-year-old boy from South Sudan presented with complaints of sudden onset, progressive bilateral lower limb weakness for the past month, inability to walk or stand without assistance, and urinary incontinence. Magnetic resonance imaging spine showed an irregular enhancing lesion within the conus. The various possibilities, such as Astrocytoma, and granulomatous disorders were considered. However, a biopsy revealed the lesion to be Conus schistosomiasis, a rare condition with only a few cases reported in children. Typical clinicoradiological presentation and the treatment paradigm have been discussed in this manuscript. Appropriate management of this lesion can avert surgical intervention needed for either a diagnosis or treatment. CONCLUSION: This case report aims to emphasize the importance of considering schistosomiasis as an important differential diagnosis of a conus intramedullary lesion, especially in patients from tropical endemic countries. The neurological recovery in this infestation is directly related to early diagnosis and treatment. Therefore, it is essential to recognize this entity, as early detection and management would result in significant neurological improvement without undergoing surgery.
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spelling pubmed-101592762023-05-05 A case report of conus intramedullary mansoni neuroschistosomiasis Mohandas, Prithvi Sarkar, Hrishikesh Jain, Deepti Sundaram, Vanaja Kate Garfin Surg Neurol Int Case Report BACKGROUND: Conus schistosomiasis is an extremely rare entity in which patients present with a wide range of neurological symptoms such as low back pain, paresthesia, fever, myalgia, paraparesis, and paraplegia. This neglected tropical parasitic disease causes significant neurological morbidity. The migration of parasitic worms and their eggs into the central nervous system can lead to profound and life-altering disabilities. Early, accurate diagnosis, and treatment can lead to the complete resolution of symptoms. CASE DESCRIPTION: A 5-year-old boy from South Sudan presented with complaints of sudden onset, progressive bilateral lower limb weakness for the past month, inability to walk or stand without assistance, and urinary incontinence. Magnetic resonance imaging spine showed an irregular enhancing lesion within the conus. The various possibilities, such as Astrocytoma, and granulomatous disorders were considered. However, a biopsy revealed the lesion to be Conus schistosomiasis, a rare condition with only a few cases reported in children. Typical clinicoradiological presentation and the treatment paradigm have been discussed in this manuscript. Appropriate management of this lesion can avert surgical intervention needed for either a diagnosis or treatment. CONCLUSION: This case report aims to emphasize the importance of considering schistosomiasis as an important differential diagnosis of a conus intramedullary lesion, especially in patients from tropical endemic countries. The neurological recovery in this infestation is directly related to early diagnosis and treatment. Therefore, it is essential to recognize this entity, as early detection and management would result in significant neurological improvement without undergoing surgery. Scientific Scholar 2023-04-21 /pmc/articles/PMC10159276/ /pubmed/37151453 http://dx.doi.org/10.25259/SNI_47_2023 Text en Copyright: © 2023 Surgical Neurology International https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Mohandas, Prithvi
Sarkar, Hrishikesh
Jain, Deepti
Sundaram, Vanaja Kate Garfin
A case report of conus intramedullary mansoni neuroschistosomiasis
title A case report of conus intramedullary mansoni neuroschistosomiasis
title_full A case report of conus intramedullary mansoni neuroschistosomiasis
title_fullStr A case report of conus intramedullary mansoni neuroschistosomiasis
title_full_unstemmed A case report of conus intramedullary mansoni neuroschistosomiasis
title_short A case report of conus intramedullary mansoni neuroschistosomiasis
title_sort case report of conus intramedullary mansoni neuroschistosomiasis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159276/
https://www.ncbi.nlm.nih.gov/pubmed/37151453
http://dx.doi.org/10.25259/SNI_47_2023
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