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Efficient coding of natural scenes improves neural system identification
Neural system identification aims at learning the response function of neurons to arbitrary stimuli using experimentally recorded data, but typically does not leverage normative principles such as efficient coding of natural environments. Visual systems, however, have evolved to efficiently process...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159360/ https://www.ncbi.nlm.nih.gov/pubmed/37093861 http://dx.doi.org/10.1371/journal.pcbi.1011037 |
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author | Qiu, Yongrong Klindt, David A. Szatko, Klaudia P. Gonschorek, Dominic Hoefling, Larissa Schubert, Timm Busse, Laura Bethge, Matthias Euler, Thomas |
author_facet | Qiu, Yongrong Klindt, David A. Szatko, Klaudia P. Gonschorek, Dominic Hoefling, Larissa Schubert, Timm Busse, Laura Bethge, Matthias Euler, Thomas |
author_sort | Qiu, Yongrong |
collection | PubMed |
description | Neural system identification aims at learning the response function of neurons to arbitrary stimuli using experimentally recorded data, but typically does not leverage normative principles such as efficient coding of natural environments. Visual systems, however, have evolved to efficiently process input from the natural environment. Here, we present a normative network regularization for system identification models by incorporating, as a regularizer, the efficient coding hypothesis, which states that neural response properties of sensory representations are strongly shaped by the need to preserve most of the stimulus information with limited resources. Using this approach, we explored if a system identification model can be improved by sharing its convolutional filters with those of an autoencoder which aims to efficiently encode natural stimuli. To this end, we built a hybrid model to predict the responses of retinal neurons to noise stimuli. This approach did not only yield a higher performance than the “stand-alone” system identification model, it also produced more biologically plausible filters, meaning that they more closely resembled neural representation in early visual systems. We found these results applied to retinal responses to different artificial stimuli and across model architectures. Moreover, our normatively regularized model performed particularly well in predicting responses of direction-of-motion sensitive retinal neurons. The benefit of natural scene statistics became marginal, however, for predicting the responses to natural movies. In summary, our results indicate that efficiently encoding environmental inputs can improve system identification models, at least for noise stimuli, and point to the benefit of probing the visual system with naturalistic stimuli. |
format | Online Article Text |
id | pubmed-10159360 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-101593602023-05-05 Efficient coding of natural scenes improves neural system identification Qiu, Yongrong Klindt, David A. Szatko, Klaudia P. Gonschorek, Dominic Hoefling, Larissa Schubert, Timm Busse, Laura Bethge, Matthias Euler, Thomas PLoS Comput Biol Research Article Neural system identification aims at learning the response function of neurons to arbitrary stimuli using experimentally recorded data, but typically does not leverage normative principles such as efficient coding of natural environments. Visual systems, however, have evolved to efficiently process input from the natural environment. Here, we present a normative network regularization for system identification models by incorporating, as a regularizer, the efficient coding hypothesis, which states that neural response properties of sensory representations are strongly shaped by the need to preserve most of the stimulus information with limited resources. Using this approach, we explored if a system identification model can be improved by sharing its convolutional filters with those of an autoencoder which aims to efficiently encode natural stimuli. To this end, we built a hybrid model to predict the responses of retinal neurons to noise stimuli. This approach did not only yield a higher performance than the “stand-alone” system identification model, it also produced more biologically plausible filters, meaning that they more closely resembled neural representation in early visual systems. We found these results applied to retinal responses to different artificial stimuli and across model architectures. Moreover, our normatively regularized model performed particularly well in predicting responses of direction-of-motion sensitive retinal neurons. The benefit of natural scene statistics became marginal, however, for predicting the responses to natural movies. In summary, our results indicate that efficiently encoding environmental inputs can improve system identification models, at least for noise stimuli, and point to the benefit of probing the visual system with naturalistic stimuli. Public Library of Science 2023-04-24 /pmc/articles/PMC10159360/ /pubmed/37093861 http://dx.doi.org/10.1371/journal.pcbi.1011037 Text en © 2023 Qiu et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Qiu, Yongrong Klindt, David A. Szatko, Klaudia P. Gonschorek, Dominic Hoefling, Larissa Schubert, Timm Busse, Laura Bethge, Matthias Euler, Thomas Efficient coding of natural scenes improves neural system identification |
title | Efficient coding of natural scenes improves neural system identification |
title_full | Efficient coding of natural scenes improves neural system identification |
title_fullStr | Efficient coding of natural scenes improves neural system identification |
title_full_unstemmed | Efficient coding of natural scenes improves neural system identification |
title_short | Efficient coding of natural scenes improves neural system identification |
title_sort | efficient coding of natural scenes improves neural system identification |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159360/ https://www.ncbi.nlm.nih.gov/pubmed/37093861 http://dx.doi.org/10.1371/journal.pcbi.1011037 |
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