Polygenic risk scores for the prediction of common cancers in East Asians: A population-based prospective cohort study

BACKGROUND: To evaluate the utility of polygenic risk scores (PRSs) in identifying high-risk individuals, different publicly available PRSs for breast (n=85), prostate (n=37), colorectal (n=22), and lung cancers (n=11) were examined in a prospective study of 21,694 Chinese adults. METHODS: We constr...

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Detalles Bibliográficos
Autores principales: Ho, Peh Joo, Tan, Iain BeeHuat, Chong, Dawn Qingqing, Khor, Chiea Chuen, Yuan, Jian-Min, Koh, Woon-Puay, Dorajoo, Rajkumar, Li, Jingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Epidemiology and Global Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159619/
https://www.ncbi.nlm.nih.gov/pubmed/36971353
http://dx.doi.org/10.7554/eLife.82608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159619/
https://www.ncbi.nlm.nih.gov/pubmed/36971353
http://dx.doi.org/10.7554/eLife.82608

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