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Craniofacial Fibrous Dysplasia: Surgical Management and Long-Term Outcomes at a Referral Center in Mexico City

Background  Craniofacial fibrous dysplasia (CFD) is an uncommon benign condition in which a bone is replaced by fibrous tissue. An adequate clinical characterization considering the number of affected bones and functional impairment is important to determine the most effective surgical intervention...

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Autores principales: Lopez-Garibay, Luis Alejandro, Guevara-Valmaña, Osvaldo, Telich-Tarriba, Jose Eduardo, Navarro-Barquín, David Felipe, Haro-Alvarez, Natalia, Andrade-Delgado, Laura, Martínez-Wagner, Rogelio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159691/
https://www.ncbi.nlm.nih.gov/pubmed/37153332
http://dx.doi.org/10.1055/s-0042-1760251
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author Lopez-Garibay, Luis Alejandro
Guevara-Valmaña, Osvaldo
Telich-Tarriba, Jose Eduardo
Navarro-Barquín, David Felipe
Haro-Alvarez, Natalia
Andrade-Delgado, Laura
Martínez-Wagner, Rogelio
author_facet Lopez-Garibay, Luis Alejandro
Guevara-Valmaña, Osvaldo
Telich-Tarriba, Jose Eduardo
Navarro-Barquín, David Felipe
Haro-Alvarez, Natalia
Andrade-Delgado, Laura
Martínez-Wagner, Rogelio
author_sort Lopez-Garibay, Luis Alejandro
collection PubMed
description Background  Craniofacial fibrous dysplasia (CFD) is an uncommon benign condition in which a bone is replaced by fibrous tissue. An adequate clinical characterization considering the number of affected bones and functional impairment is important to determine the most effective surgical intervention for its management. This study aims to present our institution's experience in the evaluation and management of CFD. Methods  This was a retrospective study that included patients with CFD managed at our institution. Data included demographic characteristics, afflicted bones, surgical procedures performed, and recurrence. Results are presented as mean and percentages. Recurrence-free years and association between the type of surgery and recurrence was evaluated. Results  Eighteen patients were included (11 females, 61%). The zygomatic, maxillary, and frontal bones were the most commonly affected with eight (18%) cases each. The most common procedure was bone burring, with 36 procedures. Recurrence was more prevalent after burring (58.3%) and occurred earlier than in the bone resection group (13 vs. 15 years, p > 0.05). Conclusion  Surgery continues to be the cornerstone of CFD treatment. Bone burring is effective for debulking and contouring but increases the risk for recurrence. An individualized approach should be tailored according to the anatomical location of the disease, type of CFD, behavior of the lesion, and accompanying clinical complaints.
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spelling pubmed-101596912023-05-05 Craniofacial Fibrous Dysplasia: Surgical Management and Long-Term Outcomes at a Referral Center in Mexico City Lopez-Garibay, Luis Alejandro Guevara-Valmaña, Osvaldo Telich-Tarriba, Jose Eduardo Navarro-Barquín, David Felipe Haro-Alvarez, Natalia Andrade-Delgado, Laura Martínez-Wagner, Rogelio Indian J Plast Surg Background  Craniofacial fibrous dysplasia (CFD) is an uncommon benign condition in which a bone is replaced by fibrous tissue. An adequate clinical characterization considering the number of affected bones and functional impairment is important to determine the most effective surgical intervention for its management. This study aims to present our institution's experience in the evaluation and management of CFD. Methods  This was a retrospective study that included patients with CFD managed at our institution. Data included demographic characteristics, afflicted bones, surgical procedures performed, and recurrence. Results are presented as mean and percentages. Recurrence-free years and association between the type of surgery and recurrence was evaluated. Results  Eighteen patients were included (11 females, 61%). The zygomatic, maxillary, and frontal bones were the most commonly affected with eight (18%) cases each. The most common procedure was bone burring, with 36 procedures. Recurrence was more prevalent after burring (58.3%) and occurred earlier than in the bone resection group (13 vs. 15 years, p > 0.05). Conclusion  Surgery continues to be the cornerstone of CFD treatment. Bone burring is effective for debulking and contouring but increases the risk for recurrence. An individualized approach should be tailored according to the anatomical location of the disease, type of CFD, behavior of the lesion, and accompanying clinical complaints. Thieme Medical and Scientific Publishers Pvt. Ltd. 2023-03-13 /pmc/articles/PMC10159691/ /pubmed/37153332 http://dx.doi.org/10.1055/s-0042-1760251 Text en Association of Plastic Surgeons of India. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Lopez-Garibay, Luis Alejandro
Guevara-Valmaña, Osvaldo
Telich-Tarriba, Jose Eduardo
Navarro-Barquín, David Felipe
Haro-Alvarez, Natalia
Andrade-Delgado, Laura
Martínez-Wagner, Rogelio
Craniofacial Fibrous Dysplasia: Surgical Management and Long-Term Outcomes at a Referral Center in Mexico City
title Craniofacial Fibrous Dysplasia: Surgical Management and Long-Term Outcomes at a Referral Center in Mexico City
title_full Craniofacial Fibrous Dysplasia: Surgical Management and Long-Term Outcomes at a Referral Center in Mexico City
title_fullStr Craniofacial Fibrous Dysplasia: Surgical Management and Long-Term Outcomes at a Referral Center in Mexico City
title_full_unstemmed Craniofacial Fibrous Dysplasia: Surgical Management and Long-Term Outcomes at a Referral Center in Mexico City
title_short Craniofacial Fibrous Dysplasia: Surgical Management and Long-Term Outcomes at a Referral Center in Mexico City
title_sort craniofacial fibrous dysplasia: surgical management and long-term outcomes at a referral center in mexico city
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159691/
https://www.ncbi.nlm.nih.gov/pubmed/37153332
http://dx.doi.org/10.1055/s-0042-1760251
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