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Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters

Vaccines play a critical role in combating the COVID-19 pandemic. Future control of the pandemic requires improved vaccines with high efficacy against newly emerging SARS-CoV-2 variants and the ability to reduce virus transmission. Here we compare immune responses and preclinical efficacy of the mRN...

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Detalles Bibliográficos
Autores principales: Nouailles, Geraldine, Adler, Julia M., Pennitz, Peter, Peidli, Stefan, Teixeira Alves, Luiz Gustavo, Baumgardt, Morris, Bushe, Judith, Voss, Anne, Langenhagen, Alina, Langner, Christine, Martin Vidal, Ricardo, Pott, Fabian, Kazmierski, Julia, Ebenig, Aileen, Lange, Mona V., Mühlebach, Michael D., Goekeri, Cengiz, Simmons, Szandor, Xing, Na, Abdelgawad, Azza, Herwig, Susanne, Cichon, Günter, Niemeyer, Daniela, Drosten, Christian, Goffinet, Christine, Landthaler, Markus, Blüthgen, Nils, Wu, Haibo, Witzenrath, Martin, Gruber, Achim D., Praktiknjo, Samantha D., Osterrieder, Nikolaus, Wyler, Emanuel, Kunec, Dusan, Trimpert, Jakob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159847/
https://www.ncbi.nlm.nih.gov/pubmed/37012419
http://dx.doi.org/10.1038/s41564-023-01352-8

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