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Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters
Vaccines play a critical role in combating the COVID-19 pandemic. Future control of the pandemic requires improved vaccines with high efficacy against newly emerging SARS-CoV-2 variants and the ability to reduce virus transmission. Here we compare immune responses and preclinical efficacy of the mRN...
Autores principales: | Nouailles, Geraldine, Adler, Julia M., Pennitz, Peter, Peidli, Stefan, Teixeira Alves, Luiz Gustavo, Baumgardt, Morris, Bushe, Judith, Voss, Anne, Langenhagen, Alina, Langner, Christine, Martin Vidal, Ricardo, Pott, Fabian, Kazmierski, Julia, Ebenig, Aileen, Lange, Mona V., Mühlebach, Michael D., Goekeri, Cengiz, Simmons, Szandor, Xing, Na, Abdelgawad, Azza, Herwig, Susanne, Cichon, Günter, Niemeyer, Daniela, Drosten, Christian, Goffinet, Christine, Landthaler, Markus, Blüthgen, Nils, Wu, Haibo, Witzenrath, Martin, Gruber, Achim D., Praktiknjo, Samantha D., Osterrieder, Nikolaus, Wyler, Emanuel, Kunec, Dusan, Trimpert, Jakob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159847/ https://www.ncbi.nlm.nih.gov/pubmed/37012419 http://dx.doi.org/10.1038/s41564-023-01352-8 |
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