Reference gene selection for clinical chimeric antigen receptor T-cell product vector copy number assays

BACKGROUND AIMS: Reference genes are an essential part of clinical assays such as droplet digital polymerase chain reaction (ddPCR), which measure the number of copies of vector integrated into genetically engineered cells and the loss of plasmids in reprogrammed cells used in clinical cell therapie...

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Detalles Bibliográficos
Autores principales: Ma, Jinxia, Shao, Lipei, Fuksenko, Tatyana, Liu, Hui, Shi, Rongye, Dinh, Anh, Highfill, Steven L., Zhang, Nan, Panch, Sandhya R., Somerville, Robert P., Stroncek, David F., Jin, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159958/
https://www.ncbi.nlm.nih.gov/pubmed/36935289
http://dx.doi.org/10.1016/j.jcyt.2023.02.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159958/
https://www.ncbi.nlm.nih.gov/pubmed/36935289
http://dx.doi.org/10.1016/j.jcyt.2023.02.010

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