Genomic mutation landscape of skin cancers from DNA repair-deficient xeroderma pigmentosum patients

Xeroderma pigmentosum (XP) is a genetic disorder caused by mutations in genes of the Nucleotide Excision Repair (NER) pathway (groups A-G) or in Translesion Synthesis DNA polymerase η (V). XP is associated with an increased skin cancer risk, reaching, for some groups, several thousand-fold compared...

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Detalles Bibliográficos
Autores principales: Yurchenko, Andrey A., Rajabi, Fatemeh, Braz-Petta, Tirzah, Fassihi, Hiva, Lehmann, Alan, Nishigori, Chikako, Wang, Jinxin, Padioleau, Ismael, Gunbin, Konstantin, Panunzi, Leonardo, Morice-Picard, Fanny, Laplante, Pierre, Robert, Caroline, Kannouche, Patricia L., Menck, Carlos F. M., Sarasin, Alain, Nikolaev, Sergey I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160032/
https://www.ncbi.nlm.nih.gov/pubmed/37142601
http://dx.doi.org/10.1038/s41467-023-38311-0

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