Re-convolving the compositional landscape of primary and recurrent glioblastoma reveals prognostic and targetable tissue states

Glioblastoma (GBM) diffusely infiltrates the brain and intermingles with non-neoplastic brain cells, including astrocytes, neurons and microglia/myeloid cells. This complex mixture of cell types forms the biological context for therapeutic response and tumor recurrence. We used single-nucleus RNA se...

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Detalles Bibliográficos
Autores principales: Al-Dalahmah, Osama, Argenziano, Michael G., Kannan, Adithya, Mahajan, Aayushi, Furnari, Julia, Paryani, Fahad, Boyett, Deborah, Save, Akshay, Humala, Nelson, Khan, Fatima, Li, Juncheng, Lu, Hong, Sun, Yu, Tuddenham, John F., Goldberg, Alexander R., Dovas, Athanassios, Banu, Matei A., Sudhakar, Tejaswi, Bush, Erin, Lassman, Andrew B., McKhann, Guy M., Gill, Brian J. A., Youngerman, Brett, Sisti, Michael B., Bruce, Jeffrey N., Sims, Peter A., Menon, Vilas, Canoll, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160047/
https://www.ncbi.nlm.nih.gov/pubmed/37142563
http://dx.doi.org/10.1038/s41467-023-38186-1

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