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Radiation therapy improves CAR T cell activity in acute lymphoblastic leukemia

Autologous T cells engineered to express a chimeric antigen receptor (CAR) specific for CD19 are approved for the treatment of various CD19(+) hematological malignancies. While CAR T cells induce objective responses in a majority of patients, relapse frequently occurs upon loss of CD19 expression by...

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Detalles Bibliográficos
Autores principales:	Sugita, Mayumi, Yamazaki, Takahiro, Alhomoud, Mohammad, Martinet, Jérémie, Latouche, Jean-Baptiste, Golden, Encouse, Boyer, Olivier, Van Besien, Koen, Formenti, Silvia C., Galluzzi, Lorenzo, Guzman, Monica L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160073/ https://www.ncbi.nlm.nih.gov/pubmed/37142568 http://dx.doi.org/10.1038/s41419-023-05829-6

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