Distinct mutational pattern of T-cell large granular lymphocyte leukemia combined with pure red cell aplasia: low mutational burden of STAT3

T-cell large granular lymphocyte leukemia (T-LGL) is often accompanied by pure red cell aplasia (PRCA). A high depth of next generation sequencing (NGS) was used for detection of the mutational profiles in T-LGL alone (n = 25) and T-LGL combined with PRCA (n = 16). Beside STAT3 mutation (41.5%), the...

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Detalles Bibliográficos
Autores principales: Park, Sooyong, Yun, Jiwon, Choi, Sung Yoon, Jeong, Dajeong, Gu, Ja-Yoon, Lee, Jee-Soo, Seong, Moon-Woo, Chang, Yoon Hwan, Yun, Hongseok, Kim, Hyun Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160083/
https://www.ncbi.nlm.nih.gov/pubmed/37142644
http://dx.doi.org/10.1038/s41598-023-33928-z

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