Reversible transitions between noradrenergic and mesenchymal tumor identities define cell plasticity in neuroblastoma

Noradrenergic and mesenchymal identities have been characterized in neuroblastoma cell lines according to their epigenetic landscapes and core regulatory circuitries. However, their relationship and relative contribution in patient tumors remain poorly defined. We now document spontaneous and revers...

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Detalles Bibliográficos
Autores principales: Thirant, Cécile, Peltier, Agathe, Durand, Simon, Kramdi, Amira, Louis-Brennetot, Caroline, Pierre-Eugène, Cécile, Gautier, Margot, Costa, Ana, Grelier, Amandine, Zaïdi, Sakina, Gruel, Nadège, Jimenez, Irène, Lapouble, Eve, Pierron, Gaëlle, Sitbon, Déborah, Brisse, Hervé J., Gauthier, Arnaud, Fréneaux, Paul, Grossetête, Sandrine, Baudrin, Laura G., Raynal, Virginie, Baulande, Sylvain, Bellini, Angela, Bhalshankar, Jaydutt, Carcaboso, Angel M., Geoerger, Birgit, Rohrer, Hermann, Surdez, Didier, Boeva, Valentina, Schleiermacher, Gudrun, Delattre, Olivier, Janoueix-Lerosey, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160107/
https://www.ncbi.nlm.nih.gov/pubmed/37142597
http://dx.doi.org/10.1038/s41467-023-38239-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160107/
https://www.ncbi.nlm.nih.gov/pubmed/37142597
http://dx.doi.org/10.1038/s41467-023-38239-5

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